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肝内胆管癌前列腺转移1例:极为罕见的病例。

A Case of Prostatic Metastasis from Intrahepatic Cholangiocarcinoma: An Extremely Rare Event.

作者信息

Aiyadurai Sanathan, Garg Tulika, Sayeed Tass, Shahbaz Zainab, Adewole Idowu O, Nguty Nkeng Enoh, Joseph Abia, Udoeyop Datiobong, Qamar Yusra, Khan Aadil

机构信息

Internal Medicine, Caribbean Medical University, Willemstad, CUW.

Medicine, Government Medical College & Hospital, Chandigarh, IND.

出版信息

Cureus. 2023 Feb 17;15(2):e35100. doi: 10.7759/cureus.35100. eCollection 2023 Feb.

DOI:10.7759/cureus.35100
PMID:36938164
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10022909/
Abstract

The second most frequent primary carcinoma of the liver to emerge is intrahepatic cholangiocarcinoma (ICC), which is thought to be an incurable, rapidly proliferating tumor with a dismal prognosis. ICC is typically found at an advanced stage and is physiologically hostile. Regional lymph nodes and liver metastases are frequent tumor metastatic sites for ICC and serve as indicators of tumor recurrence. ICC metastasizing to the male urogenital tract has only seldom been documented. Typically, lymph vessels serve as the primary pathway for disseminating tumor cells. The high fatality rate associated with ICC and the rapid spread of the disease may be caused by this lymphatic route. The only curative therapeutic approach for treating these tumors is surgical removal. We report a case of prostatic metastasis from ICC.

摘要

第二常见的原发性肝癌是肝内胆管癌(ICC),它被认为是一种无法治愈、迅速增殖且预后不佳的肿瘤。ICC通常在晚期被发现,并且在生理上具有侵袭性。区域淋巴结和肝转移是ICC常见的肿瘤转移部位,也是肿瘤复发的指标。ICC转移至男性泌尿生殖道的情况鲜有报道。通常,淋巴管是肿瘤细胞播散的主要途径。与ICC相关的高死亡率和疾病的快速传播可能是由这条淋巴途径所致。治疗这些肿瘤的唯一治愈性治疗方法是手术切除。我们报告一例肝内胆管癌前列腺转移的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63e0/10022909/d6de341cf648/cureus-0015-00000035100-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63e0/10022909/eea0e4ca9de8/cureus-0015-00000035100-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63e0/10022909/2ca1f295cdb2/cureus-0015-00000035100-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63e0/10022909/d6de341cf648/cureus-0015-00000035100-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63e0/10022909/eea0e4ca9de8/cureus-0015-00000035100-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63e0/10022909/2ca1f295cdb2/cureus-0015-00000035100-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63e0/10022909/d6de341cf648/cureus-0015-00000035100-i03.jpg

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本文引用的文献

1
Current Targeted Therapy Options in the Treatment of Cholangiocarcinoma: A Literature Review.胆管癌治疗中的当前靶向治疗选择:文献综述
Cureus. 2022 Jun 23;14(6):e26233. doi: 10.7759/cureus.26233. eCollection 2022 Jun.
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Intrahepatic cholangiocarcinoma: Tumour heterogeneity and its clinical relevance.肝内胆管癌:肿瘤异质性及其临床相关性。
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Prostatic metastasis from intrahepatic cholangiocarcinoma.肝内胆管癌的前列腺转移
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Epidemiology of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.肝细胞癌和肝内胆管癌的流行病学
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Randomized trial comparing conventional-dose with high-dose conformal radiation therapy in early-stage adenocarcinoma of the prostate: long-term results from proton radiation oncology group/american college of radiology 95-09.随机对照试验比较常规剂量与高剂量适形放疗在早期前列腺腺癌:来自质子放射肿瘤学组/美国放射学院 95-09 的长期结果。
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