Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA.
Department of Environmental Medicine, New York University Grossman School of Medicine, New York, NY, USA.
Arch Environ Occup Health. 2023;78(4):206-211. doi: 10.1080/19338244.2023.2185191. Epub 2023 Mar 20.
Asthma is defined as a heterogeneous disease with respiratory symptoms (wheeze, shortness of breath, chest tightness and cough) that vary over time and intensity, and variable expiratory airflow limitation. Environmental and occupational exposures contribute to its causation. WTC-related or aggravated asthma is considered a World Trace Center (WTC) Health Program certifiable disease. Criteria include defined exposures to the WTC dust and fumes, the presence of symptoms, or aggravated symptoms that are present within 5 years after the last potential for WTC dust/fume exposures (the last 9/11 exposures occurred on July 31, 2002), and a WTC-provider diagnosis of asthma. Asthma is the 3 most common non-cancer certification among WTC responders and survivors. In this review we provide evidence-based information on the evaluation, diagnosis, and treatment of patients with WTC-related or aggravated asthma and include peer-reviewed research findings in WTC-exposed populations.
哮喘被定义为一种具有呼吸道症状(喘息、呼吸急促、胸闷和咳嗽)的异质性疾病,这些症状随时间和强度而变化,并伴有呼气气流受限。环境和职业暴露是其病因之一。与 WTC 相关或加重的哮喘被认为是 WTC 健康计划可认证的疾病。标准包括接触 WTC 粉尘和烟雾、存在症状或加重症状,这些症状出现在最后一次接触 WTC 粉尘/烟雾的 5 年内(最后一次 9/11 接触发生在 2002 年 7 月 31 日),并且 WTC 提供者诊断为哮喘。哮喘是 WTC responder 和幸存者中第三常见的非癌症认证。在这篇综述中,我们提供了关于评估、诊断和治疗与 WTC 相关或加重的哮喘患者的循证信息,并包括了在 WTC 暴露人群中的同行评审研究结果。