Sa'adah M A, Shakir R A, Jadaa S I, Bezjak V, Araj G F
University Department of Neurology, IbnSina Hospital, Kuwait.
J Infect. 1987 Nov;15(3):263-8. doi: 10.1016/s0163-4453(87)92803-9.
A 39-year-old previously healthy patient with combined pulmonary and neural cryptococcosis was successfully managed by pulmonary resection and antifungal chemotherapy. The pulmonary mass was removed under cover of miconazole and 5-fluorocytosine even though the patient had concomitant active meningitis. He recovered dramatically after the surgical procedure and remained well 2 years later. We suggest that, as in our patient, early removal of a pulmonary cryptococcal mass under antifungal cover may in other similar patients obviate the need for protracted antifungal therapy and lead to an excellent response of the neural cryptococcosis.
