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衰弱、年龄、美国麻醉医师协会(ASA)分级及体重指数对下颌骨骨折切开复位内固定术后发病率的影响

Frailty, Age, ASA Classification, and BMI on Postoperative Morbidity in Mandibular Fracture ORIF.

作者信息

Nguyen Theodore V, Torabi Sina J, Goshtasbi Khodayar, Lonergan Ashley R, Salehi Parsa P, Haidar Yarah M, Tjoa Tjoson, Kuan Edward C

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, Irvine, California, USA.

Department of Surgery, Division of Otolaryngology, Yale School of Medicine, New Haven, Connecticut, USA.

出版信息

Otolaryngol Head Neck Surg. 2023 May;168(5):1006-1014. doi: 10.1002/ohn.181. Epub 2023 Jan 22.

Abstract

OBJECTIVE

To assess how traditional, simple markers of health independently affect postoperative morbidity of mandibular fracture open reduction-internal fixations (ORIFs).

STUDY DESIGN

Cohort study.

SETTING

National Surgical Quality Improvement Project (NSQIP) Database.

METHODS

The 2005 to 2017 NSQIP database was queried for patients who underwent mandibular ORIF. To control for the severity of the trauma, an additional "concurrent surgery" variable was created. A modified 5-item frailty index was calculated based on the following: presurgery-dependent functional status, chronic hypertension, diabetes mellitus, history of chronic obstructive pulmonary disease, and history of congestive heart failure.

RESULTS

Among 1806 patients with mandibular ORIFs (mean age 34.8 ± 15.4 years), modified frailty index (mFI) was associated with 30-day medical complications (p < .001), reoperation (p < .001), and readmission (p = .005) on univariate analysis. Increased age was associated with prolonged hospitalization (p < .001) and medical complications (p < .001). The increased American Society of Anesthesiologists (ASA) score was associated with all endpoints (p ≤ .003), while increased body mass index (BMI) was associated with none. On multivariate analysis, only increased ASA was associated with any adverse event (reference: ASA 1; ASA 2, odds ratio [OR]: 2.17 [95% confidence interval, CI: 2.17-3.71], p = .004; ASA 3-4, OR: 3.63 [95% CI: 1.91-6.91], p < .001). Similarly, mFI and BMI were not independently associated with prolonged hospitalization (≥2 days) (p ≥ .015), but 65+ age (reference: 18-49; OR: 2.33 [95% CI: 1.40-3.86], p = .001) and ASA 3 to 4 groups (reference: ASA 1; OR: 3.26 [95% CI: 2.06-5.14], p < .001) were.

CONCLUSION

ASA status and age are more useful modalities than mFI or BMI in predicting poor postoperative morbidity in mandibular ORIF. These simple metrics can assist with managing surgeons' expectations for mandibular ORIF patients.

摘要

目的

评估传统的简单健康指标如何独立影响下颌骨骨折切开复位内固定术(ORIF)的术后发病率。

研究设计

队列研究。

研究地点

国家外科质量改进项目(NSQIP)数据库。

方法

查询2005年至2017年NSQIP数据库中接受下颌骨ORIF手术的患者。为控制创伤的严重程度,创建了一个额外的“同期手术”变量。基于以下因素计算改良的5项衰弱指数:术前依赖的功能状态、慢性高血压、糖尿病、慢性阻塞性肺疾病史和充血性心力衰竭史。

结果

在1806例下颌骨ORIF患者(平均年龄34.8±15.4岁)中,单因素分析显示改良衰弱指数(mFI)与30天医疗并发症(p<0.001)、再次手术(p<0.001)和再次入院(p=0.005)相关。年龄增加与住院时间延长(p<0.001)和医疗并发症(p<0.001)相关。美国麻醉医师协会(ASA)评分增加与所有终点相关(p≤0.003),而体重指数(BMI)增加与任何终点均无关。多因素分析显示,只有ASA增加与任何不良事件相关(参考:ASA 1;ASA 2,比值比[OR]:2.17[95%置信区间,CI:2.17 - 3.71],p = 0.004;ASA 3 - 4,OR:3.63[95% CI:1.91 - 6.91],p<0.001)。同样,mFI和BMI与住院时间延长(≥2天)无独立相关性(p≥0.015),但65岁及以上年龄组(参考:18 - 49岁;OR:2.33[95% CI:1.40 - 3.86],p = 0.001)和ASA 3至4组(参考:ASA 1;OR:3.26[95% CI:2.06 - 5.14],p<0.001)与住院时间延长相关。

结论

在预测下颌骨ORIF术后不良发病率方面,ASA状态和年龄比mFI或BMI更有用。这些简单指标可帮助外科医生管理对下颌骨ORIF患者的预期。

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