Department of Neurosurgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Department of Neurosurgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan; Department of Neurosurgery, Stanford University, Palo Alto, California, USA.
World Neurosurg. 2023 Aug;176:e40-e48. doi: 10.1016/j.wneu.2023.03.063. Epub 2023 Mar 20.
Tuberculum sellae meningiomas (TSMs) have traditionally been removed using a transcranial approach. In recent years, endoscopic surgery for TSMs has been reported with an expansion of indications.
We have performed a fully endoscopic supraorbital keyhole approach for small to medium-sized TSMs and performed radical tumor removal similar to conventional transcranial procedure. We report the details of this surgical procedure including cadaveric stepwise dissection and initial surgical results for small to medium-sized TSMs.
We used an endoscopic supraorbital eyebrow approach for 6 patients with TSMs between September 2020 and September 2022. Mean tumor diameter was 16.0 mm (range, 10-20 mm). The surgical approach included an eyebrow skin incision ipsilateral to the lesion, a small frontal craniotomy, subfrontal exposure of the lesion, removal of the tuberculum sellae, unroofing of the optic canal, and resection of the tumor. The extent of resection, preoperative and postoperative visual function, complications, and operative time were evaluated.
Optic canal involvement was observed in all patients. Two patients (33%) showed visual dysfunction before surgery. Simpson grade 1 tumor resection was achieved in all cases. Visual function was improved in 2 cases, and remained unchanged in 4 cases. Postoperative pituitary function was preserved in all cases, with no decreases in olfaction.
The endoscopic supraorbital eyebrow approach for TSMs allowed resection of the lesion, including tumor extending to the optic canal, with a good surgical view. This technique is minimally invasive for patients and may represent a good surgical option for medium-sized TSMs.
鞍结节脑膜瘤(TSMs)传统上采用经颅入路切除。近年来,内镜手术治疗 TSM 的适应证不断扩大。
我们采用经眶上锁孔内镜入路治疗中小型 TSM,实现与传统经颅手术相似的根治性肿瘤切除。我们报告了这种手术方法的详细情况,包括尸体分步解剖和用于治疗中小型 TSM 的初步手术结果。
我们在 2020 年 9 月至 2022 年 9 月期间使用经眶上锁孔内镜入路治疗了 6 例 TSM 患者。平均肿瘤直径为 16.0 毫米(范围,10-20 毫米)。手术入路包括病变对侧的眉弓皮肤切口、小范围额骨开颅、眶额部暴露病变、切除鞍结节、视神经管开窗和肿瘤切除。评估了切除程度、术前和术后视力功能、并发症和手术时间。
所有患者均有视神经管受累。2 例患者(33%)术前存在视力障碍。所有病例均实现了 Simpson 分级 1 级肿瘤切除。2 例患者的视力得到改善,4 例患者保持不变。所有病例术后垂体功能均得以保留,嗅觉无下降。
经眶上锁孔内镜入路治疗 TSM 可切除病变,包括延伸至视神经管的肿瘤,具有良好的手术视野。该技术对患者微创,可能是治疗中小型 TSM 的一种良好手术选择。