Casey Bradley, Hofstrand Reese, Patel Divyang, Bahekar Amol, Chapa-Rodriguez Alejandro
Internal Medicine, Cape Fear Valley Medical Center, Fayetteville, USA.
Cardiology, Cape Fear Valley Medical Center, Fayetteville, USA.
Cureus. 2023 Feb 15;15(2):e35034. doi: 10.7759/cureus.35034. eCollection 2023 Feb.
Renal tubular acidosis (RTA) refers to a group of disorders in which the elimination of hydrogen ions from the kidney or the reabsorption of filtered bicarbonate is impaired, resulting in metabolic acidosis. Hypokalemia is also prominent in different types of RTA. We are presenting an interesting case about a chronic alcoholic patient who presented to the emergency department and was found to be severely hypokalemic. During her hospital stay, she had multiple cardiac arrests likely secondary to her hypokalemia despite adequate treatment with potassium supplementation. We came to the conclusion of distal RTA in our patient based on hyperchloremic metabolic acidosis, sodium bicarbonate of 10 mmol/L, low potassium, blood urea nitrogen, and creatinine within normal limits, alkaline urine, and a positive urinary anion gap. It is likely that the cause of our patient's underlying type 1 RTA was secondary to her chronic alcohol abuse. Her potassium eventually returned to baseline, and she was discharged.
肾小管酸中毒(RTA)是指一组疾病,其中肾脏排氢离子或重吸收滤过的碳酸氢盐功能受损,导致代谢性酸中毒。低钾血症在不同类型的RTA中也很突出。我们现报告一例有趣的病例,一名慢性酒精中毒患者到急诊科就诊,发现严重低钾血症。在她住院期间,尽管补充钾进行了充分治疗,但她仍多次发生心脏骤停,可能继发于低钾血症。根据高氯性代谢性酸中毒、碳酸氢钠10 mmol/L、低钾、血尿素氮和肌酐在正常范围内、碱性尿以及尿阴离子间隙阳性,我们得出患者为远端RTA的结论。我们患者潜在的1型RTA的病因可能继发于她长期酗酒。她的钾最终恢复到基线水平,随后出院。