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双侧肾上腺增生所致原发性醛固酮增多症。基于一例病例及文献复习的研究(作者译)

[Primary hyperaldosteronism due to bilateral adrenal hyperplasia of the adrenals. Study based upon one case and a review of the literature (author's transl)].

作者信息

Herpin D, Corvol P, Sudre Y, Demange J

出版信息

Ann Med Interne (Paris). 1978 Oct;129(10):557-64.

PMID:369425
Abstract

The authors report the case of a 41-year-old man suffering from primary hyperaldosteronism due to bilateral adrenal hyperplasia, predominantly on the left. This condition is somewhat less common than Conn's adenoma and differs distinctly on the basis of a very poor response to surgical treatment. It can generally be diagnosed by non-invasive techniques, the most reliable of which are the postural test and adrenal isotope scan under inhibition with dexamethasone. These methods are nevertheless not always valuable in the presence of certain forms of hyperplasia which are less distinct from an anatomical standpoint, and must then be complemented by adrenal phlebography and estimation of aldosterone in adrenal venous blood or, if this proves impossible, in the inferior vena cava and renal veins.

摘要

作者报告了一例41岁男性因双侧肾上腺增生(主要是左侧)导致原发性醛固酮增多症的病例。这种情况比Conn腺瘤稍少见,并且由于对手术治疗反应很差而明显不同。一般可通过非侵入性技术诊断,其中最可靠的是体位试验和地塞米松抑制下的肾上腺同位素扫描。然而,在某些从解剖学角度不太明显的增生形式存在时,这些方法并不总是有价值的,此时必须辅以肾上腺静脉造影和肾上腺静脉血中醛固酮的测定,如果无法做到这一点,则测定下腔静脉和肾静脉中的醛固酮。

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