Laboratory of Comorbidity in Cardiovascular Diseases, Federal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases", 6, Sosnoviy Blvd, Kemerovo, Russian Federation, 650002.
Myski City Hospital, Polyclinic No. 1, 23, Pervomajskaya St., Myski, Kemerovo Region, Russian Federation, 652849.
Sci Rep. 2023 Mar 21;13(1):4628. doi: 10.1038/s41598-023-31834-y.
Aim of this study was to compare right ventricular echocardiography parameters in urbanized hypertensive patients of the Shor and non-indigenous ethnic groups in the Mountain Shoria region. The study included patients with arterial hypertension: 58 Shors and 50 non-indigenous urbanized residents, comparable in age, and divided by ethnicity and gender into 4 groups: Shors men (n = 20), Shors women (n = 38) , non-indigenous men (n = 15) and non-indigenous women (n = 35). All underwent echocardiographic examination, and the right heart parameters were studied. Shor men with arterial hypertension had the lowest values of the pulmonary artery index (p = 0.05), the right atrium dimensions (p = 0.04), and the highest values of the blood flow velocity in the right ventricle, et' (p = 0.05) and st' (p = 0.05) in comparison with non-indigenous men. Shor women have the lowest values Et/At ratios (p = 0.05). RV diastolic dysfunction was detected mainly in women compared with men (23.1% and 1.9%, p = 0.0014), somewhat more often in Shors. Ethnicity was one of the factors associated with the right ventricular diastolic dysfunction presence (p = 0.002). Among the factors associated with the RV diastolic dysfunction were risk factors (smoking, obesity), blood pressure, gender, ethnicity, and left ventricular parameters (diastolic dysfunction and the myocardial mass increase). Thus, our study established the influence of ethnic differences on the right heart echocardiographic parameters in Shors and Caucasians with arterial hypertension. The effect of sex on RV diastolic dysfunction was a lot bigger compared to the effect of ethnicity. The revealed differences should improve the assessment of the right heart structure and function in patients with arterial hypertension from small ethnic groups, which will help to improve the diagnosis and treatment of such patients.
本研究旨在比较城市高血压患者的右心超声心动图参数，这些患者分别来自山区肖尔族和非土著少数民族。研究对象包括：58 名肖尔族高血压患者和 50 名非土著城市居民，他们在年龄方面具有可比性，并根据种族和性别分为 4 组：肖尔族男性（n=20）、肖尔族女性（n=38）、非土著男性（n=15）和非土著女性（n=35）。所有患者均接受了超声心动图检查，并研究了右心参数。与非土著男性相比，患有高血压的肖尔族男性肺动脉指数（p=0.05）、右心房尺寸（p=0.04）最低，而右心室血流速度 Et'（p=0.05）和 st'（p=0.05）最高。肖尔族女性的 Et/At 比值最低（p=0.05）。与男性相比，女性主要存在右心室舒张功能障碍（23.1%和 1.9%，p=0.0014），而且在肖尔族女性中更为常见。种族是与右心室舒张功能障碍存在相关的因素之一（p=0.002）。与右心室舒张功能障碍相关的因素包括：危险因素（吸烟、肥胖）、血压、性别、种族和左心室参数（舒张功能障碍和心肌质量增加）。因此，我们的研究确立了种族差异对高血压的肖尔族和高加索人右心超声心动图参数的影响。与种族相比，性别对 RV 舒张功能障碍的影响更大。所揭示的差异应改善对来自小种族群体的高血压患者的右心结构和功能的评估，这将有助于改善此类患者的诊断和治疗。
