Fu Xuerong, Li Mingxing
Department of Ultrasound, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
J Coll Physicians Surg Pak. 2023 Mar;33(3):352-354. doi: 10.29271/jcpsp.2023.03.352.
To observe the association between migraine and patent foramen ovale (PFO) using contrast-enhanced transthoracic echocardiography (cTTE). Eighty-five migraine with aura (MA) patients and 85 migraine without aura (MO) patients from January 2020 to February 2022 were divided into group A and group B, respectively. Sixty-five healthy people were included in normal control group. Difference of PFO positive rate among group A, group B, and normal control group was significant (p=0.002). Difference of PFO related right-to-left shunt (PFO-RLS), Grade 2 shunt, and Grade 3 shunt among group A, group B, and normal control group was significant (p=0.043 and p=0.013 respectively). PFO-RLS Grade 2 and 3 shunts may play an important role in MA patients and MO patients, and the size of PFO-RLS shunt may be associated with migraine. Key Words: Migraine, Patent foramen ovale (PFO), Right-to-left shunt (RLS), Contrast-enhanced transthoracic echocardiography (cTTE).
采用经胸超声心动图造影（cTTE）观察偏头痛与卵圆孔未闭（PFO）之间的关联。将2020年1月至2022年2月的85例有先兆偏头痛（MA）患者和85例无先兆偏头痛（MO）患者分别分为A组和B组。正常对照组纳入65名健康人。A组、B组和正常对照组之间的PFO阳性率差异有统计学意义（p = 0.002）。A组、B组和正常对照组之间的PFO相关右向左分流（PFO-RLS）、2级分流和3级分流差异有统计学意义（分别为p = 0.043和p = 0.013）。PFO-RLS 2级和3级分流可能在MA患者和MO患者中起重要作用，且PFO-RLS分流大小可能与偏头痛有关。关键词：偏头痛；卵圆孔未闭（PFO）；右向左分流（RLS）；经胸超声心动图造影（cTTE）
