Treatment of periorbital syringomas with intradermal botulinum toxin A monotherapy versus carbon dioxide laser: a case report.

Syringomas are eccrine-derived benign adnexal neoplasms with the highest prevalence in early adulthood. They predominantly occur in females. They are commonly located on the face, particularly the lower eyelids, which have a high demand for cosmetic enhancement. Periorbital syringomas continue to pose a therapeutic challenge, with no consistently effective treatment available. Intradermal injection of botulinum toxin A is one of the new treatment modalities for periorbital syringomas. We report a case of periorbital syringomas in a 53-year-old female patient successfully treated using intradermal botulinum toxin A monotherapy as a painless cost-effective treatment that produced better long-term results than carbon dioxide laser.