Elousrouti Layla Tahiri, Gouzi Imane, Hammas Naoual, Chbani Laila, Tazi Fadl, Fareh Moulay Hassan, Elfatemi Hinde
Department of Pathology, Hospital University Hassan II, KM 2.200 Sidi Harazem Street, 30070 Fez, Morocco.
Laboratory of Biomedical and Translational Research, Faculty of Medicine and Pharmacology, Sidi Mohamed Ben Abdellah University, KM 2.200 Sidi Harazem Street, 30070 Fez, Morocco.
Int J Surg Pathol. 2023 Dec;31(8):1580-1585. doi: 10.1177/10668969231160256. Epub 2023 Mar 22.
The myoid gonadal stromal tumor is a very rare testicular spindle cell tumor. Few cases have been reported in the literature from 1977 to 2022. It was an emerging entity in the fourth edition of the WHO Classification of Tumors of the Urinary System and Male Genital Organs and has been instated as a full benign entity in the new edition of 2022. We report herein an additional case of a myoid gonadal stromal tumor. It was a 27-year-old man who presented with an asymptomatic mass in his left testicle for 2 months. The mass was confirmed by ultrasound as a 3 cm solid well-circumscribed lesion for which orchiectomy has been performed. The histological analysis of the specimen and the immunohistochemistry staining was consistent with a myoid gonadal stromal tumor. The characteristics of this tumor are summarized in well-circumscribed, nonencapsulated masses of uniform spindle cells, and immunohistochemically, tumor cells coexpress SMA and S-100 protein. The benign behavior of this tumor is demonstrated by our results and those presented in the previous cases reported in the literature.
肌样性腺间质肿瘤是一种非常罕见的睾丸梭形细胞瘤。1977年至2022年的文献中报道的病例很少。它是《世界卫生组织泌尿系统及男性生殖器官肿瘤分类》第四版中出现的一个新病种，并在2022年新版中被确认为完全良性的肿瘤。我们在此报告一例肌样性腺间质肿瘤。患者为一名27岁男性，左侧睾丸无症状肿块2个月。超声检查证实该肿块为一个3厘米大小、边界清晰的实性病变，已行睾丸切除术。标本的组织学分析和免疫组化染色结果与肌样性腺间质肿瘤一致。该肿瘤的特征总结为边界清晰、无包膜的均匀梭形细胞肿块，免疫组化显示肿瘤细胞共表达平滑肌肌动蛋白（SMA）和S-100蛋白。我们的结果以及文献中先前报道的病例结果均表明该肿瘤具有良性行为。
