Department of Medicine, Surgery and Neurosciences, Unit of General Surgery and Surgical Oncology, University of Siena, Strada Delle Scotte, 4, 53100, Siena, Italy.
World J Surg. 2023 Jul;47(7):1713-1720. doi: 10.1007/s00268-023-06975-w. Epub 2023 Mar 22.
Identification of reliable risk-stratification tools is critical for surgical decision making, particularly in frail and elderly. The aim of the study is to validate the Emergency Surgery Frailty Index (EmSFI), in over 65 years old patients operated on for acute appendicitis.
An observational study was conducted enrolling elderly patients with diagnosis of acute appendicitis who underwent emergency appendicectomy or right colectomy, between 2016 and 2021. All patients were treated according to the last SIFIPAC/WSES/SICG/SIMEU guidelines.
Overall, 61 patients were analyzed. Complication rate was higher for patients in the second EmSFI risk Class. Moreover, ROC analyses identified 3 as the best cutoff value in predicting risk of adverse postoperative events. Complication rate was higher in oldest elderly patients-over 80 years-(42.9 vs 22.5%; p 0.05) and was mainly related to medical complications (42.9 vs 12.5%, p 0.007). However, intestinal obstruction, peri-appendicular abscess on preoperative CT, peritonitis and a longer duration of surgery are related with increased risk of complications in the group of patients under 80 years.
The EmSFI score results a valid prognostic marker for frailty status, and it may support the surgeon in emergency setting for acute appendicitis. Patients aged 80 years or older have a higher risk of complications, independent from those factors which relate to increased morbidity in younger elderly patients. Age alone is not a reliable indicator of the real surgical risk, but it must encourage the adoption of multidisciplinary collaborative models of care for this group of patients.
对于手术决策,尤其是对于虚弱和老年患者,识别可靠的风险分层工具至关重要。本研究旨在验证适用于 65 岁以上因急性阑尾炎行手术治疗患者的紧急手术虚弱指数(EmSFI)。
本观察性研究纳入了 2016 年至 2021 年间诊断为急性阑尾炎并接受急诊阑尾切除术或右结肠切除术的老年患者。所有患者均根据最新的 SIFIPAC/WSES/SICG/SIMEU 指南进行治疗。
共分析了 61 例患者。第二 EmSFI 风险等级的患者并发症发生率更高。此外,ROC 分析确定 3 为预测不良术后事件风险的最佳截断值。80 岁以上的高龄患者并发症发生率更高(42.9%比 22.5%,p=0.05),且主要与医疗并发症相关(42.9%比 12.5%,p=0.007)。然而,在年龄低于 80 岁的患者中,肠梗阻、术前 CT 提示阑尾周围脓肿、腹膜炎和手术时间延长与并发症风险增加相关。
EmSFI 评分是虚弱状态的有效预后标志物,它可以在急性阑尾炎的紧急情况下为外科医生提供支持。80 岁或以上的患者并发症风险较高,这与增加年轻老年患者发病率的因素无关。年龄本身并不是真实手术风险的可靠指标,但它必须鼓励为这组患者采用多学科协作的护理模式。