Cellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran.
Department of Medical Parasitology and Mycology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Environ Monit Assess. 2023 Mar 22;195(4):499. doi: 10.1007/s10661-023-11097-w.
Cryptosporidium is an obligate intracellular parasite reported from all over the world. This protozoan infects a wide range of animals as well as humans. Cryptosporidium parvum and Cryptosporidium hominis are the most prevalent infecting species with mild and self-limiting infection in healthy people. The protozoan oocyst is resistant to common water purifiers. Based on emerging evidence, Cryptosporidium is one of waterborne parasites considered a major public health problem in developing and developed countries. In this study, 42 samples were collected from 14 rivers in the catchment area of Lake Urmia in northwest of Iran. Moreover, amplification of SSU rRNA gene was performed, and polymerase chain reaction products were sequenced. The results of sequencing and comparing the sequences with those in the GenBank revealed that all the 17 positive samples were C. parvum, a zoonotic species and one of the most frequent human-infecting species. Considering these data, it is highly important to inhibit the spread of this protozoan by treating livestock and preventing human and animal effluents from entering the water.
隐孢子虫是一种专性细胞内寄生虫，在世界各地都有报道。这种原生动物感染范围广泛，包括多种动物以及人类。微小隐孢子虫和人隐孢子虫是最常见的感染物种，在健康人群中感染通常较轻且具有自限性。该原生动物的卵囊对常见的水净化剂具有抗性。基于新出现的证据，隐孢子虫是一种水生寄生虫，被认为是发展中国家和发达国家的主要公共卫生问题之一。在这项研究中，从伊朗西北部乌尔米亚湖集水区的 14 条河流中采集了 42 个样本。此外，还进行了 SSU rRNA 基因的扩增，并对聚合酶链反应产物进行了测序。测序结果与 GenBank 中的序列进行比较后显示，所有 17 个阳性样本均为微小隐孢子虫，这是一种人畜共患的物种，也是最常感染人类的物种之一。考虑到这些数据，通过对牲畜进行治疗以及防止人类和动物的污水进入水中来抑制这种原生动物的传播是非常重要的。
