Division of Neurology, Department of Medicine, Jichi Medical University, Japan.
Department of Internal Medicine, Imai Hospital, Japan.
Intern Med. 2023 Nov 1;62(21):3247-3250. doi: 10.2169/internalmedicine.1236-22. Epub 2023 Mar 22.
Rivastigmine is a highly effective drug for treating Alzheimer's disease. However, its addiction can be fatal, so proper use of this transdermal drug is needed. We herein report an 85-year-old woman with Alzheimer's disease who inappropriately placed rivastigmine patches on the back of her neck. She suffered from acute cholinergic syndrome, hypersalivation, anorexia, dyspnea, and vomiting. These symptoms disappeared when the improper use of rivastigmine patches was ceased. This case serves as a warning to physicians and pharmacists of the risk associated with the improper placement of rivastigmine patches.
利斯的明是一种治疗阿尔茨海默病的高效药物。然而，它有成瘾性，可能致命，因此需要正确使用这种透皮药物。我们在此报告一例 85 岁女性阿尔茨海默病患者，她将利斯的明贴片不当贴在颈后。她出现了急性胆碱能综合征，表现为流涎、厌食、呼吸困难和呕吐。停止使用利斯的明贴片后，这些症状消失。此病例提醒医生和药剂师注意利斯的明贴片不当放置的风险。
