Joslin Diabetes Center; Beth Israel Deaconess Medical Center; Harvard Medical School, One Joslin Place, Boston, MA 02215, USA.
Endocrinol Metab Clin North Am. 2023 Jun;52(2):389-403. doi: 10.1016/j.ecl.2022.10.006. Epub 2023 Feb 16.
The number of older adults with type 1 diabetes (T1D) is increasing due to an overall increase in life expectancy and improvement in diabetes management and treatment of complications. They are a heterogeneous cohort due to the dynamic process of aging and the presence of comorbidities and diabetes-related complications. A high risk for hypoglycemia unawareness and severe hypoglycemia has been described. Periodic assessment of health status and adjustment of glycemic goals to mitigate hypoglycemia is imperative. Continuous glucose monitoring, insulin pump, and hybrid closed-loop systems are promising tools to improve glycemic control and mitigate hypoglycemia in this age group.
由于预期寿命的延长以及糖尿病管理和并发症治疗的改善,患有 1 型糖尿病(T1D)的老年患者人数正在增加。由于衰老的动态过程以及合并症和糖尿病相关并发症的存在,他们是一个异质的群体。低血糖意识不足和严重低血糖的风险较高。定期评估健康状况并调整血糖目标以减轻低血糖至关重要。连续血糖监测、胰岛素泵和混合闭环系统是改善该年龄段血糖控制和减轻低血糖的有前途的工具。