俄勒冈州波特兰市注射吸毒者对人类免疫缺陷病毒暴露前预防的认知。
Human immunodeficiency virus pre-exposure prophylaxis awareness among people who inject drugs in Portland, Oregon.
机构信息
Department of Medicine, Oregon Health & Science University, Portland, OR, USA.
Public Health Division, HIV/STD/TB Program, Oregon Health Authority, Portland, OR, USA.
出版信息
Int J STD AIDS. 2023 Jul;34(8):567-573. doi: 10.1177/09564624231154302. Epub 2023 Mar 22.
BACKGROUND
Pre-Exposure Prophylaxis (PrEP) to prevent transmission of human immunodeficiency virus (HIV) among people who inject drugs (PWID) has demonstrated efficacy yet awareness of PrEP among PWID is low.
METHODS
2018 National Behavioral Health Survey data from the Portland, Oregon metropolitan statistical area was analyzed with chi-squared tests and generalized linear models to determine correlates of PrEP awareness among PWID.
RESULTS
80% of the sample had at least one indication for PrEP and 15% of the sample was aware of PrEP. Factors associated with higher PrEP awareness were: higher education level (PR = 1.083, CI = 1.018-1.153, = .012), reporting transactional sex (PR = 1.154, CI = 1.019-1.307, = .024), and men who have sex with men reporting condomless sex (PR = 1.376, CI = 1.081-1.752, = .010). Lack of a usual source of care (PR = 0.884, CI = 0.824-0.949, < .001) was negatively associated with PrEP awareness.
CONCLUSIONS
Interventions to increase PrEP awareness need to target groups with particularly low awareness and be delivered in settings accessible to PWID.
背景
预防人类免疫缺陷病毒（HIV）传播的暴露前预防（PrEP）在注射毒品者（PWID）中已被证明有效，但 PWID 对 PrEP 的认识很低。
方法
分析俄勒冈州波特兰都会统计区 2018 年国家行为健康调查数据，采用卡方检验和广义线性模型，确定 PWID 对 PrEP 认识的相关因素。
结果
80%的样本至少有一个 PrEP 适应证，15%的样本知道 PrEP。与更高的 PrEP 意识相关的因素包括：更高的教育水平（PR = 1.083，CI = 1.018-1.153，P =.012）、报告易性交易（PR = 1.154，CI = 1.019-1.307，P =.024）和男男性行为者报告无保护性行为（PR = 1.376，CI = 1.081-1.752，P =.010）。缺乏常规医疗来源（PR = 0.884，CI = 0.824-0.949，P <.001）与 PrEP 意识呈负相关。
结论
为了提高 PrEP 的认识，需要针对认识特别低的群体进行干预，并在 PWID 可获得的环境中进行。
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