Li Xiaona, Li Ruili, Lian Qiguo, Wang Yang, Gu Wenkui, Meng Qinghe
Beichen District Center for Disease Control and Prevention, Tianjin, China.
Children Health and Development Department, Capital Institute of Paediatrics, Beijing, China.
Can J Infect Dis Med Microbiol. 2023 Mar 13;2023:5262117. doi: 10.1155/2023/5262117. eCollection 2023.
To describe the epidemiological characteristics and transmission dynamics of SARS-CoV-2 Omicron variant during "Dynamic Zero" period, we analyzed data on the 108 laboratory-confirmed SARS-CoV-2 cases during 14 to 30 May 2022 in Beichen district, Tianjin, China. We collected information on demographic characteristics, exposure history, and illness timelines of the 108 cases. We described characteristics of the patients and estimated the key epidemiological parameters, including serial interval and the time-dependent reproduction number of the Omicron variant, Rt. Among the 108 laboratory-confirmed patients, the median age was 38 years old, and 50.9% were females. Obvious symptoms were observed among 67.6% (73/108) of all cases, and major clinical manifestations included fever, sore throat, and cough, which occurred in 31.5%, 26.9%, and 19.4% of the 108 cases, respectively. The mean and standard deviation of the SI were estimated as 2.89 and 0.95 days, the Rt varied from 1.24 to 0.27 for a 7-day timelapse. The low reproduction number and the Omicron outbreak being suppressed within a short time marked the effectiveness of the implemented public health measures, such as nucleic acid screening, social distancing, masking, vaccination, medical treatment of patients, and isolation of close contacts. These measures play an important role in fulfilling the goal of controlling the spread of the disease.
为描述严重急性呼吸综合征冠状病毒2(SARS-CoV-2)奥密克戎变异株在“动态清零”期间的流行病学特征和传播动态,我们分析了2022年5月14日至30日中国天津市北辰区108例实验室确诊SARS-CoV-2病例的数据。我们收集了这108例病例的人口统计学特征、暴露史和发病时间线信息。我们描述了患者的特征,并估计了关键流行病学参数,包括奥密克戎变异株的代间距和随时间变化的繁殖数Rt。在108例实验室确诊患者中,年龄中位数为38岁,女性占50.9%。67.6%(73/108)的病例出现明显症状,主要临床表现包括发热、咽痛和咳嗽,分别占108例病例的31.5%、26.9%和19.4%。代间距的均值和标准差估计分别为2.89天和0.95天,Rt在7天时间间隔内从1.24变化到0.27。低繁殖数以及奥密克戎疫情在短时间内得到抑制,标志着实施的公共卫生措施(如核酸筛查、社交距离、戴口罩、疫苗接种、患者治疗以及密切接触者隔离)的有效性。这些措施在实现控制疾病传播的目标方面发挥着重要作用。