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Context is key for FLT3-ITD.

作者信息

Meyer Sara E

机构信息

Thomas Jefferson University.

出版信息

Blood. 2023 Mar 23;141(12):1373-1374. doi: 10.1182/blood.2022019135.

Abstract
摘要

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本文引用的文献

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Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.
Cancer Cell. 2015 Apr 13;27(4):502-15. doi: 10.1016/j.ccell.2015.03.009.
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NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.
Exp Hematol. 2014 Feb;42(2):101-13.e5. doi: 10.1016/j.exphem.2013.10.005. Epub 2013 Oct 29.
5
FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
Cell Rep. 2013 Jun 27;3(6):1766-76. doi: 10.1016/j.celrep.2013.04.031. Epub 2013 May 30.
7
Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.
Blood. 2012 Mar 22;119(12):2883-94. doi: 10.1182/blood-2011-10-382283. Epub 2012 Feb 8.
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Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model.
Blood. 2008 Apr 1;111(7):3849-58. doi: 10.1182/blood-2007-08-109942. Epub 2008 Feb 1.
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FLT3-ITD cooperates with inv(16) to promote progression to acute myeloid leukemia.
Blood. 2008 Feb 1;111(3):1567-74. doi: 10.1182/blood-2006-06-030312. Epub 2007 Oct 29.

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