Genesiscare, Spain.
Ghent University/Ghent University Hospital, Ghent, Belgium.
Breast. 2023 Jun;69:299-305. doi: 10.1016/j.breast.2023.03.009. Epub 2023 Mar 17.
Given that most local relapses of breast cancer occur proximal to the original location of the primary, the delivery of additional radiation dose to breast tissue that contained the original primary cancer (known as a "boost") has been a standard of care for some decades. In the context of falling relapse rates, however, it is an appropriate time to re-evaluate the role of the boost. This article reviews the evolution of the radiotherapy boost in breast cancer, discussing who to boost and how to boost in the 2020s, and arguing that, in both cases, less is more.
鉴于大多数乳腺癌的局部复发发生在原发性肿瘤的原始位置附近，因此在含有原发性癌症的乳房组织（称为“boost”）中给予额外的放射剂量一直是几十年的护理标准。然而，在复发率下降的情况下，现在是重新评估 boost 作用的适当时机。本文回顾了乳腺癌放疗 boost 的发展历程，讨论了在 2020 年代应该给谁 boost 以及如何 boost，并认为在这两种情况下，越少越好。
