• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Germline STAT6 gain-of-function variants cause severe allergy.

作者信息

Yamashita Motoi, Morio Tomohiro

机构信息

Laboratory for Transcriptional Regulation, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan; Department of Pediatrics and Developmental Biology, Graduate School of Medicaddl and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Department of Pediatrics and Developmental Biology, Graduate School of Medicaddl and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

J Allergy Clin Immunol. 2023 May;151(5):1252-1254. doi: 10.1016/j.jaci.2023.03.007. Epub 2023 Mar 21.

DOI:10.1016/j.jaci.2023.03.007
PMID:36958638
Abstract
摘要

相似文献

1
Germline STAT6 gain-of-function variants cause severe allergy.生殖系 STAT6 功能获得性变异导致严重过敏。
J Allergy Clin Immunol. 2023 May;151(5):1252-1254. doi: 10.1016/j.jaci.2023.03.007. Epub 2023 Mar 21.
2
Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond.信号转导和转录激活因子6(STAT6)的人类种系功能获得:从严重过敏性疾病到淋巴瘤及其他。
Trends Immunol. 2024 Feb;45(2):138-153. doi: 10.1016/j.it.2023.12.003. Epub 2024 Jan 17.
3
Learning while treating: Gain-of-function STAT6 variants in severe allergic disease.治疗中学习:严重过敏疾病中的功能获得性 STAT6 变体。
Cell Rep Med. 2023 May 16;4(5):101040. doi: 10.1016/j.xcrm.2023.101040.
4
Severe allergic dysregulation due to a gain of function mutation in the transcription factor STAT6.由于转录因子 STAT6 功能获得性突变导致严重过敏失调。
J Allergy Clin Immunol. 2023 Jul;152(1):182-194.e7. doi: 10.1016/j.jaci.2023.01.023. Epub 2023 Feb 8.
5
STAT6 joins the gain-of-function club.信号转导及转录激活因子6(STAT6)加入了功能获得性俱乐部。
J Allergy Clin Immunol. 2023 Jul;152(1):53-55. doi: 10.1016/j.jaci.2023.05.003. Epub 2023 May 14.
6
A germline STAT6 gain-of-function variant is associated with early-onset allergies.一种生殖系 STAT6 功能获得性变异与早发性过敏相关。
J Allergy Clin Immunol. 2023 Feb;151(2):565-571.e9. doi: 10.1016/j.jaci.2022.09.028. Epub 2022 Oct 7.
7
STAT6 gain-of-function variant exacerbates multiple allergic symptoms.STAT6 功能获得性变异加重多种过敏症状。
J Allergy Clin Immunol. 2023 May;151(5):1402-1409.e6. doi: 10.1016/j.jaci.2022.12.802. Epub 2022 Dec 17.
8
Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease.人类种系杂合功能获得性 STAT6 变体导致严重的过敏疾病。
J Exp Med. 2023 May 1;220(5). doi: 10.1084/jem.20221755. Epub 2023 Mar 8.
9
Association of STAT6 gene variants with food allergy diagnosed by double-blind placebo-controlled food challenges.STAT6 基因变异与双盲安慰剂对照食物激发试验诊断的食物过敏的关联。
Allergy. 2018 Jun;73(6):1337-1341. doi: 10.1111/all.13432. Epub 2018 Apr 6.
10
IL-4Rα Inhibition for Severe "Eosinophilic Gastroenteritis, Allergy, and Anaphylaxis" Syndrome due to a Gain-of-Function Variant in STAT6.针对由STAT6功能获得性变异导致的严重“嗜酸性粒细胞性胃肠炎、过敏和过敏反应”综合征的IL-4Rα抑制作用
J Clin Immunol. 2023 Dec 22;44(1):29. doi: 10.1007/s10875-023-01639-9.

引用本文的文献

1
T2-driven manifestations of inborn errors of immunity.免疫缺陷病的T2驱动表现。
J Allergy Clin Immunol. 2024 Aug;154(2):245-254. doi: 10.1016/j.jaci.2024.05.007. Epub 2024 May 17.
2
STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.STAT6 通过抑制脂肪酸氧化介导线粒体转位促进草酸钙晶体沉积诱导的肾纤维化。
Inflamm Res. 2023 Dec;72(12):2111-2126. doi: 10.1007/s00011-023-01803-2. Epub 2023 Nov 4.