Anderson Orthopaedic Research Institute, Alexandria, Virginia; Inova Mount Vernon Hospital Joint Replacement Center, Alexandria, Virginia.
Anderson Orthopaedic Research Institute, Alexandria, Virginia.
J Arthroplasty. 2023 Jun;38(6S):S42-S46. doi: 10.1016/j.arth.2023.03.036. Epub 2023 Mar 21.
Short-acting spinal anesthetics enable rapid recovery after hip and knee arthroplasty; however, concerns with transient neurological symptoms (TNS) cause some to avoid using lidocaine. Postoperative urinary retention (POUR) is also a concern with spinal anesthesia. We sought to study the comparative rates of TNS and POUR between lidocaine, mepivacaine, and bupivacaine in a high-volume hip and knee arthroplasty setting.
Data for 1,217 primary THA, TKA, and unicompartmental knee arthroplasty cases were reviewed and grouped by spinal anesthetic agent (lidocaine, mepivacaine, or bupivacaine). Of the 1,217 cases, utilization was 523 lidocaine, 573 mepivacaine, and 121 bupivacaine. The incidence of TNS and POUR requiring catheterization was measured both by clinical evaluation as well as a questionnaire sent to patients 14 days postoperatively.
The overall rate of TNS was 8%. With the numbers available, there was no difference in rates of TNS between groups (6.9% lidocaine, 9.2% mepivacaine, and 4.1% bupivacaine; P = .297). There was no difference in rates of TNS or POUR between THA and TKA/unicompartmental knee arthroplasty. Bupivacaine had a significantly higher rate of urinary retention (9.1%; P < .001) than mepivacaine (2.8%) or lidocaine (1.5%).
This study showed no difference in the rate of TNS between the 3 common agents used in spinal anesthesia. Short-acting spinal anesthetics such as lidocaine and mepivacaine can lower the rate of POUR requiring catheterization, helping to enable rapid recovery after hip and knee arthroplasty.
短效椎管内麻醉可使髋关节和膝关节置换术后快速恢复;然而,一些人担心短暂性神经症状(TNS)而避免使用利多卡因。椎管内麻醉后还存在尿潴留(POUR)的问题。我们旨在研究在高容量髋关节和膝关节置换手术环境中,利多卡因、甲哌卡因和布比卡因之间 TNS 和 POUR 的相对发生率。
对 1217 例初次全髋关节置换术(THA)、全膝关节置换术(TKA)和单髁膝关节置换术(UKA)病例的数据进行了回顾,并根据椎管内麻醉药物(利多卡因、甲哌卡因或布比卡因)进行分组。在 1217 例病例中,利多卡因使用率为 523 例,甲哌卡因使用率为 573 例,布比卡因使用率为 121 例。通过临床评估和术后 14 天向患者发送问卷来测量 TNS 和需要导尿的 POUR 的发生率。
总体 TNS 发生率为 8%。根据现有数据,各组间 TNS 发生率无差异(利多卡因组为 6.9%,甲哌卡因组为 9.2%,布比卡因组为 4.1%;P=0.297)。THA 和 TKA/UKA 之间 TNS 或 POUR 发生率无差异。布比卡因的尿潴留发生率(9.1%)明显高于甲哌卡因(2.8%)或利多卡因(1.5%)(P<0.001)。
本研究表明,在椎管内麻醉中使用的 3 种常用药物之间 TNS 发生率无差异。短效椎管内麻醉剂,如利多卡因和甲哌卡因,可降低需要导尿的 POUR 发生率,有助于髋关节和膝关节置换术后快速恢复。