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乳腺癌转移至胸腺。

Breast cancer metastasis to thymus.

机构信息

Breast Radiology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK

Breast Radiology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.

出版信息

BMJ Case Rep. 2023 Mar 23;16(3):e254374. doi: 10.1136/bcr-2022-254374.

DOI:10.1136/bcr-2022-254374
PMID:36958759
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10040002/
Abstract

Despite advancements in breast cancer management, metastatic disease remains a challenge. Thymic metastasis is an infrequent site of involvement. We intend to report a rare case of a woman in her 40s who presented with bilateral nipple discharge for 2 months. A triple assessment confirmed left breast carcinoma. A staging CT scan and positron emission tomography scan revealed an anterior mediastinal mass of thymic origin, and histology confirmed metastatic breast cancer. The patient made a good recovery following surgical and oncological treatment.

摘要

尽管乳腺癌的治疗取得了进展,但转移性疾病仍然是一个挑战。胸腺转移是一种罕见的受累部位。我们旨在报告一例罕见病例,患者为 40 多岁女性,双侧乳头溢液 2 个月。三联评估证实左侧乳腺癌。分期 CT 扫描和正电子发射断层扫描显示前纵隔胸腺来源的肿块,组织学证实为转移性乳腺癌。患者在接受手术和肿瘤治疗后恢复良好。

相似文献

1
Breast cancer metastasis to thymus.乳腺癌转移至胸腺。
BMJ Case Rep. 2023 Mar 23;16(3):e254374. doi: 10.1136/bcr-2022-254374.
2
Role of flourine-18 fluorodeoxyglucose positron emission tomography in thymic pathology.氟-18氟脱氧葡萄糖正电子发射断层扫描在胸腺病理学中的作用。
Eur J Cardiothorac Surg. 2007 Apr;31(4):731-6. doi: 10.1016/j.ejcts.2007.01.024. Epub 2007 Feb 9.
3
Differentiation of normal thymus from anterior mediastinal lymphoma and lymphoma recurrence at pediatric PET/CT.小儿 PET/CT 中正常胸腺与前纵隔淋巴瘤及淋巴瘤复发的鉴别诊断。
Radiology. 2012 Feb;262(2):613-22. doi: 10.1148/radiol.11110715. Epub 2011 Dec 12.
4
Diagnostic and functional imaging of thymic and mediastinal involvement in lymphoproliferative disorders.淋巴增生性疾病中胸腺和纵隔受累情况的诊断及功能成像
Clin Imaging. 2014 Nov-Dec;38(6):771-84. doi: 10.1016/j.clinimag.2014.05.012. Epub 2014 Jun 4.
5
Merkel Cell Carcinoma of Unknown Primary Origin.原发灶不明的 Merkel 细胞癌。
Acta Dermatovenerol Croat. 2023 Dec;31(3):153-155.
6
Thymic metastasis of breast cancer 22 years after surgery: a case report.乳腺癌术后22年发生胸腺转移:一例报告
Asian J Endosc Surg. 2013 Nov;6(4):330-2. doi: 10.1111/ases.12060.
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Mediastinal and retroperitoneal fibrosis as a manifestation of breast cancer metastasis: A case report and literature review.纵隔和腹膜后纤维化作为乳腺癌转移的一种表现:一例病例报告及文献综述
Medicine (Baltimore). 2018 Aug;97(32):e11842. doi: 10.1097/MD.0000000000011842.
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False-negative rate after positron emission tomography/computer tomography scan for mediastinal staging in cI stage non-small-cell lung cancer.cI 期非小细胞肺癌纵隔分期正电子发射断层扫描/计算机断层扫描的假阴性率。
Eur J Cardiothorac Surg. 2012 Jul;42(1):93-100; discussion 100. doi: 10.1093/ejcts/ezr272. Epub 2012 Jan 20.
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Mediastinal metastasis of the thyroid papillary carcinoma mimicking thymoma.甲状腺乳头状癌纵隔转移酷似胸腺瘤
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10
Thymic teratoma or thymic remnant attached to mediastinal teratoma? The cellular origin of mediastinal teratomas revisited.胸腺畸胎瘤还是附着于纵隔畸胎瘤的胸腺残余?纵隔畸胎瘤的细胞起源再探讨。
Eur J Pediatr Surg. 2004 Apr;14(2):117-9. doi: 10.1055/s-2004-817842.

本文引用的文献

1
Rare sites of breast cancer metastasis: a review.乳腺癌转移的罕见部位:综述
Transl Cancer Res. 2019 Oct;8(Suppl 5):S518-S552. doi: 10.21037/tcr.2019.07.24.
2
Thymic function affects breast cancer development and metastasis by regulating expression of thymus secretions PTMα and Tβ15b1.胸腺功能通过调节胸腺分泌物PTMα和Tβ15b1的表达来影响乳腺癌的发展和转移。
Transl Oncol. 2021 Jan;14(1):100980. doi: 10.1016/j.tranon.2020.100980. Epub 2020 Dec 11.
3
Distinct Pattern of Metastases in Patients with Invasive Lobular Carcinoma of the Breast.乳腺浸润性小叶癌患者转移的独特模式。
Geburtshilfe Frauenheilkd. 2017 Jun;77(6):660-666. doi: 10.1055/s-0043-109374. Epub 2017 Jun 28.
4
Solitary thymic metastasis of breast cancer 13 years after surgery.乳腺癌术后13年出现孤立性胸腺转移。
Asian Cardiovasc Thorac Ann. 2017 Jul;25(6):469-471. doi: 10.1177/0218492317716586. Epub 2017 Jun 12.
5
Oligometastatic breast cancer: A mini review.寡转移乳腺癌:一篇综述
Indian J Med Paediatr Oncol. 2014 Jul;35(3):203-6. doi: 10.4103/0971-5851.142035.
6
Metastatic patterns of breast cancer subtypes: what radiologists should know in the era of personalized cancer medicine.乳腺癌亚型的转移模式:在个性化癌症医学时代放射科医生应了解的内容。
Clin Radiol. 2015 Jan;70(1):1-10. doi: 10.1016/j.crad.2014.08.015. Epub 2014 Oct 7.
7
Thymic metastasis of breast cancer 22 years after surgery: a case report.乳腺癌术后22年发生胸腺转移:一例报告
Asian J Endosc Surg. 2013 Nov;6(4):330-2. doi: 10.1111/ases.12060.
8
Thymic stromal lymphopoietin is a key mediator of breast cancer progression.胸腺基质淋巴细胞生成素是乳腺癌进展的关键介质。
J Immunol. 2011 May 15;186(10):5656-62. doi: 10.4049/jimmunol.1100463. Epub 2011 Apr 13.
9
Thymic metastasis in breast cancer: a case report.乳腺癌的胸腺转移:一例报告
Korean J Radiol. 2007 Jul-Aug;8(4):360-3. doi: 10.3348/kjr.2007.8.4.360.
10
The reticulum of lymph nodes in mice studied with the electron microscope.用电子显微镜研究小鼠淋巴结的网状组织。
Am J Anat. 1962 May;110:217-57. doi: 10.1002/aja.1001100303.