Department of Orthopaedics, Peking University Third Hospital, Beijing, China.
Ministry of Education, Engineering Research Center of Bone and Joint Precision Medicine, Beijing, China.
Orthop Surg. 2023 May;15(5):1219-1227. doi: 10.1111/os.13702. Epub 2023 Mar 23.
The spine is the most common site of bone metastases. Many cancer patients will ultimately develop spinal metastatic disease with symptomatic epidural spinal cord compression. At present, the main treatment for cervical spine tumors is surgical resection combined with postoperative radiotherapy. Implant materials for cervical spine anterior column reconstruction need to meet amounts of different properties, such as biocompatibility, bioactivity and the ability to maintain long-term mechanical strength. The selection of different materials determines the surgical efficacy and prognosis of patients to a certain extent. This article provides an overview of a variety of implant materials used for anterior column reconstruction after cervical spine tumor resection, introduces and analyzes their properties, advantages, disadvantages, derivatives, and applications in clinical practice, and looks forward to the future development of implant materials.
脊柱是最常见的骨转移部位。许多癌症患者最终会出现症状性硬膜外脊髓压迫的脊柱转移疾病。目前,颈椎肿瘤的主要治疗方法是手术切除联合术后放疗。颈椎前柱重建的植入材料需要满足大量不同的特性,如生物相容性、生物活性和长期保持机械强度的能力。不同材料的选择在一定程度上决定了患者的手术效果和预后。本文综述了颈椎肿瘤切除术后用于前柱重建的各种植入材料,介绍和分析了它们的特性、优缺点、衍生材料及其在临床实践中的应用,并对植入材料的未来发展进行了展望。