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快中子束治疗应用中剂量测定协议的一致性。

Uniformity in dosimetry protocols for therapeutic applications of fast neutron beams.

作者信息

Mijnheer B J, Wootton P, Williams J R, Eenmaa J, Parnell C J

机构信息

Netherlands Cancer Institute, Amsterdam.

出版信息

Med Phys. 1987 Nov-Dec;14(6):1020-6. doi: 10.1118/1.595980.

Abstract

In this supplement to both the American and the European protocols for clinical neutron dosimetry, new recommendations are given with respect to the basic physical parameters and experimental techniques employed. For neutron dosimetry, the air kerma or exposure calibration in a photon beam is the most suitable method for the calibration of tissue-equivalent ionization chambers until calibration in a standard neutron field becomes available. More recent data are recommended for the physical parameters required for the photon calibration as well as for the measurements in the neutron beam. Water is recommended as the reference phantom material due to its similarity in absorption and scattering properties to muscle. The resulting overall change in absorbed dose calculated according to this supplement, compared with the original protocols, will be smaller than about +/- 2% due to differences in the basic physical parameters. An additional change of several percent occurs at depth in a phantom as a result of the difference between water and the muscle-equivalent liquid formerly recommended as the reference phantom material.

摘要

在这份针对美国和欧洲临床中子剂量测定协议的补充文件中,给出了关于所采用的基本物理参数和实验技术的新建议。对于中子剂量测定,在光子束中进行空气比释动能或照射量校准是校准组织等效电离室的最合适方法,直到在标准中子场中进行校准成为可能。对于光子校准所需的物理参数以及中子束中的测量,推荐使用更新的数据。由于水在吸收和散射特性方面与肌肉相似,因此推荐将水作为参考体模材料。根据本补充文件计算得出的吸收剂量与原始协议相比,由于基本物理参数的差异,总体变化将小于约±2%。由于水与先前推荐作为参考体模材料的肌肉等效液体之间的差异,在体模深度处还会出现几个百分点的额外变化。

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