Murphy Andrea L, Suh Sowon, Gillis Louise, Morrison Jason, Gardner David M
College of Pharmacy, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Department of Psychiatry, Dalhousie University, Halifax, NS B3H 2E2, Canada.
Pharmacy (Basel). 2023 Feb 27;11(2):45. doi: 10.3390/pharmacy11020045.
Long-acting injectable antipsychotics (LAIAs) have demonstrated positive outcomes for people with serious mental illnesses. They are underused, and access to LAIAs can be challenging. Pharmacies could serve as suitable environments for LAIA injection by pharmacists. To map and characterize the literature regarding the administration of LAIAs by pharmacists, a scoping review was conducted. Electronic-database searches (e.g., PsycINFO, Ovid Medline, Scopus, and Embase) and others including ProQuest Dissertations & Theses Global and Google, were conducted. Citation lists and cited-reference searches were completed. Zotero was used as the reference-management database. Covidence was used for overall review management. Two authors independently screened articles and performed full-text abstractions. From all sources, 292 studies were imported, and 124 duplicates were removed. After screening, 13 studies were included for abstraction. Most articles were published in the US since 2010. Seven studies used database and survey methods, with adherence and patient satisfaction as the main patient-outcomes assessed. Reporting of pharmacists' and patients' perspectives surrounding LAIA administration was minimal and largely anecdotal. Financial analyses for services were also limited. The published literature surrounding pharmacist administration of LAIAs is limited, providing little-to-no guidance for the development and implementation of this service by others.
长效注射用抗精神病药物(LAIA)已被证明对患有严重精神疾病的患者有积极效果。然而,这类药物的使用不足,且获取LAIA可能具有挑战性。药房可以成为药剂师进行LAIA注射的合适场所。为了梳理和描述有关药剂师管理LAIA的文献,我们进行了一项范围综述。我们进行了电子数据库搜索(如PsycINFO、Ovid Medline、Scopus和Embase)以及其他搜索,包括ProQuest Dissertations & Theses Global和谷歌。完成了引文列表和被引参考文献搜索。使用Zotero作为参考文献管理数据库。使用Covidence进行整体综述管理。两位作者独立筛选文章并进行全文摘要。从所有来源共导入292项研究,去除了124项重复研究。筛选后,纳入13项研究进行摘要。大多数文章自2010年以来在美国发表。七项研究使用了数据库和调查方法,主要评估的患者结局是依从性和患者满意度。关于药剂师和患者围绕LAIA给药的观点的报道极少,且大多是轶事性的。对服务的财务分析也很有限。关于药剂师管理LAIA的已发表文献有限,几乎没有为其他人开展和实施这项服务提供指导。