Department of Biotechnology, University of Engineering and Management, Kolkata University Area, Plot, Street Number 03, Action Area III, B/5, Newtown, Kolkata, West Bengal, 700156, India.
Appl Biochem Biotechnol. 2023 Jun;195(6):3653-3670. doi: 10.1007/s12010-023-04439-4. Epub 2023 Mar 24.
COVID-19 infection is a new disease and our knowledge is limited; day in and day out more and more interesting yet diverse observations are reported by the different research groups from different corners of the world. So, there is an urgent requirement of the invention of some effective and efficient drugs that can carry out the end of the deadly viral infection. Throughout the world, there have been many efforts carried out in different labs to invent such a drug and also identifying any pre-existing drugs which can carry out the killing of the virus. In this review, an effort has been made to understand the potential drugs which can be used against the SARS-CoV-2 viral infection. Again, the strategies on the current and the future drug discovery mechanisms against the SARS-CoV-2 are also mentioned. The different drugs made and the drugs re-used and also the drugs which are in the making process in different research laboratories across the world are also mentioned. To combat this unexpected crisis, we still need some more efforts from the different scientific communities around the world for finding a cure against this viral infection and this is needed to be done for the prevention of more loss of human life.
新型冠状病毒(COVID-19)感染是一种新出现的疾病,我们的知识有限。来自世界各地不同研究小组的报告不断有更多有趣且多样化的观察结果出现。因此,迫切需要发明一些有效且高效的药物来终结这种致命的病毒感染。在全球范围内,不同实验室已经开展了许多工作来发明此类药物,并确定任何现有的可用于杀死病毒的药物。在这篇综述中,我们努力了解可用于对抗 SARS-CoV-2 病毒感染的潜在药物。此外,还提到了针对 SARS-CoV-2 的当前和未来药物发现机制的策略。还提到了在世界各地不同研究实验室中制造的不同药物、重新使用的药物以及正在研发中的药物。为了应对这场意料之外的危机,我们仍然需要来自世界各地不同科学界的更多努力,以找到针对这种病毒感染的治疗方法,这是为了防止更多的生命损失,需要尽快完成。