Chalusa Morris, Khuluza Felix, Bandawe Chiwoza
Pathology Department, College of Medicine, University of Malawi, Blantyre, Malawi.
Mulanje District Hospital, Ministry of Health, Lilongwe, Malawi.
PLOS Glob Public Health. 2022 Nov 16;2(11):e0001274. doi: 10.1371/journal.pgph.0001274. eCollection 2022.
Antimicrobial resistance is an emerging problem in low- and middle-income countries. The problem is exacerbated by inappropriate prescription of antimicrobials. Factors that lead to overuse or inappropriate prescription of antimicrobials by the cadre of medical assistants, clinical technicians and clinical officers have received limited attention. This study investigated factors that influence prescription behaviours of antimicrobials among clinical officers in various health facilities in Mulanje district, Southern Malawi.
Qualitative study design exploring determinants of antimicrobial prescription from May to October, 2019, was used. In-depth interviews (n = 18) and focus group discussions (n = 2) were conducted with medical assistant (MA), clinical technicians and clinical officers (CO) from four health facilities in Mulanje district. COs are licensed medical practitioners with an initial three-year training and one-year internship while MAs are licensed medical practitioners with initial two-year training and one year internship. Purposive sampling was done to arrive at a sample size of 30 health cadres.
Participants pointed out that patient preferences, beliefs and clinicians' inadequate education on this issue were among the factors that contribute to inappropriate antimicrobial prescription. 75% of clinicians showed lack of knowledge on the definition of antibiotic and antimicrobial resistance.
Inappropriate use of antimicrobials is facilitated by prescription decisions made by clinicians who are greatly influenced by their patients. Interventions aimed at improving antimicrobial prescription should target both clinicians and patients.
抗菌药物耐药性在低收入和中等收入国家正成为一个新出现的问题。抗菌药物的不适当处方加剧了这一问题。导致医疗助理、临床技术员和临床干事过度使用或不适当处方抗菌药物的因素受到的关注有限。本研究调查了马拉维南部穆兰杰区各卫生机构临床干事抗菌药物处方行为的影响因素。
采用定性研究设计,探讨2019年5月至10月抗菌药物处方的决定因素。对穆兰杰区四个卫生机构的医疗助理(MA)、临床技术员和临床干事(CO)进行了深入访谈(n = 18)和焦点小组讨论(n = 2)。临床干事是经过三年初始培训和一年实习的有执照的执业医生,而医疗助理是经过两年初始培训和一年实习的有执照的执业医生。采用目的抽样法确定了30名卫生干部的样本量。
参与者指出,患者的偏好、信念以及临床医生在这个问题上教育不足是导致不适当抗菌药物处方的因素。75%的临床医生对抗生素和抗菌药物耐药性的定义缺乏了解。
临床医生受患者影响很大而做出的处方决定助长了抗菌药物的不当使用。旨在改善抗菌药物处方的干预措施应针对临床医生和患者。