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Significant response to targeted treatment with alectinib for intramedullary pediatric spinal high-grade glioma with ALK fusion.

作者信息

Ringel Amit, Elhasid Ronit, Constantini Shlomi, Roth Jonathan, Dvir Rina

机构信息

Department of Pediatric Hemato-Oncology, Dana Children's Hospital, Tel Aviv Medical Center, Tel Aviv, Israel.

Deparment of Pediatric Neurosurgery, Tel Aviv Medical Center, Tel Aviv, Israel.

出版信息

Pediatr Blood Cancer. 2023 Jul;70(7):e30312. doi: 10.1002/pbc.30312. Epub 2023 Mar 25.

DOI:10.1002/pbc.30312
PMID:36965191
Abstract
摘要

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Significant response to targeted treatment with alectinib for intramedullary pediatric spinal high-grade glioma with ALK fusion.对于伴有ALK融合的小儿脊髓高级别胶质瘤,使用阿来替尼进行靶向治疗有显著反应。
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Treatment Sequencing in Patients with Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer in Japan: A Real-World Observational Study.日本间变性淋巴瘤激酶阳性非小细胞肺癌患者的治疗序贯:一项真实世界观察性研究。
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Pediatric-type high-grade glioma of the spinal cord in the molecular era: institutional case series and updated systematic review of the literature.分子时代的小儿型脊髓高级别胶质瘤:机构病例系列及文献的最新系统综述
Childs Nerv Syst. 2025 Jun 2;41(1):200. doi: 10.1007/s00381-025-06856-8.
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Frequent detection of genetic aberrations reveals novel pathogenesis and treatment modalities in systemic juvenile xanthogranuloma.频繁检测到的基因畸变揭示了系统性幼年性黄色肉芽肿的新发病机制和治疗方式。
Pediatr Investig. 2023 Aug 28;7(3):212-215. doi: 10.1002/ped4.12398. eCollection 2023 Sep.