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Covid-19 孕妇的膈肌厚度与疾病严重程度的关系。

The relationship between diaphragm thickness and the severity of the disease in pregnant patients with Covid-19.

机构信息

Department of Obstetrics and Gynecology, Ministry of Health Ankara City Hospital, Ankara, Turkey.

Department of Radiology, Ministry of Health Ankara City Hospital, Ankara, Turkey.

出版信息

Taiwan J Obstet Gynecol. 2023 Mar;62(2):275-279. doi: 10.1016/j.tjog.2022.10.008. Epub 2022 Dec 8.

Abstract

OBJECTIVE

We aimed to investigate whether there is a relationship between diaphragm thickness and disease severity in Covid-19 pregnant subgroups.

MATERIAL AND METHODS

In this prospective study 100 pregnant patients were enrolled. Thickness of the diaphragm muscle at end-expiration was measured using B-Mode US. Hemoglobin,WBC, NLR, procalcitonin and LDH levels were measured.

RESULTS

There was a statistically significant difference between the groups in terms of diaphragm thickness, and the diaphragm thickness was thinner in the severe disease group (p < 0.001). There was no statistically significant difference between the groups with mild to moderate disease severity (p = 0.708).

CONCLUSION

Covid-19 patients who developed serious infection has thinner diaphragms than those who did not. Low diaphragm muscle thickness at the outset of Covid-19 disease, may predispose to poor clinical outcomes. Diaphragmatic ultrasound may be a promising tool to evaluate the risk of Covid-19 disease severity.

摘要

目的

我们旨在研究新冠病毒感染孕妇亚组中,膈肌厚度与疾病严重程度之间是否存在关联。

材料和方法

本前瞻性研究纳入了 100 名孕妇。使用 B 型超声测量膈肌在呼气末期的厚度。测量血红蛋白、白细胞、中性粒细胞与淋巴细胞比值、降钙素原和乳酸脱氢酶水平。

结果

两组之间的膈肌厚度存在统计学显著差异,重症组的膈肌厚度更薄(p<0.001)。而在轻至中度疾病严重程度的组之间无统计学显著差异(p=0.708)。

结论

与未发生严重感染的新冠病毒患者相比,发生严重感染的新冠病毒患者的膈肌更薄。新冠病毒疾病发病初期膈肌肌肉厚度较低,可能导致不良的临床结局。膈肌超声可能是评估新冠病毒疾病严重程度风险的有前途的工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eee/9729641/d66d5abb88f6/gr1_lrg.jpg

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