创伤性脑损伤的灌注成像
Perfusion Imaging of Traumatic Brain Injury.
作者信息
Churchill Nathan W, Graham Simon J, Schweizer Tom A
机构信息
Neuroscience Research Program, Saint Michael's Hospital, 209 Victoria Street, Toronto, ON M5B 1M8, Canada; Keenan Research Centre for Biomedical Science of St. Michael's Hospital, 209 Victoria Street, Toronto, ON M5B 1M8, Canada; Physics Department, Toronto Metropolitan University, 60 St George St, Toronto, ON M5S 1A7, Canada.
Department of Medical Biophysics, University of Toronto, 101 College Street, Suite 15-701, Toronto, ON M5G 1L7, Canada; Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Wellness Way, Toronto, ON M4N 3M5, Canada; Physical Sciences Platform, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada.
出版信息
Neuroimaging Clin N Am. 2023 May;33(2):315-324. doi: 10.1016/j.nic.2023.01.006.
The mechanisms for regulating cerebral blood flow (CBF) are highly sensitive to traumatic brain injury (TBI). The perfusion imaging technique may be used to assess CBF and identify perfusion abnormalities following a TBI. Studies have identified CBF disturbances across the injury severity spectrum and correlations with both acute and long-term indices of clinical outcome. Although not yet widely used in the clinical context, this is an important area of ongoing research.
调节脑血流量（CBF）的机制对创伤性脑损伤（TBI）高度敏感。灌注成像技术可用于评估脑血流量，并识别创伤性脑损伤后的灌注异常。研究已经确定了损伤严重程度范围内的脑血流量紊乱，以及与临床结果的急性和长期指标的相关性。尽管尚未在临床环境中广泛应用，但这是一个正在进行研究的重要领域。
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