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Single cell proteogenomic analysis of aberrant monocytosis in TET2 mutant premalignant and malignant hematopoiesis.

作者信息

Lasho Terra, Finke Christy, Timm Michael, Tefferi Ayalew, Mangaonkar Abhishek, Olteanu Horatiu, Reichard Kaaren, Ketterling Rhett, Gangat Naseema, Xie Zhuoer, Fernandez Jenna, Chia Nicholas, Gaspar-Maia Alexandre, Binder Moritz, Patnaik Mrinal M

机构信息

Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.

Department of Laboratory Medicine and Pathology, Hematopathology, Mayo Clinic, Rochester, MN, USA.

出版信息

Leukemia. 2023 Jun;37(6):1384-1387. doi: 10.1038/s41375-023-01887-z. Epub 2023 Mar 25.

DOI:10.1038/s41375-023-01887-z
PMID:36966263
Abstract
摘要

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Leuk Res. 2022 May;116:106818. doi: 10.1016/j.leukres.2022.106818. Epub 2022 Feb 22.
2
The Challenge of Distinguishing Cell-Cell Complexes from Singlet Cells in Non-Imaging Flow Cytometry and Single-Cell Sorting.在非成像流式细胞术和单细胞分选中区分细胞-细胞复合物与单细胞的挑战。
Cytometry A. 2020 Nov;97(11):1127-1135. doi: 10.1002/cyto.a.24027. Epub 2020 May 13.
3
Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)-a study of 1084 patients.
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Leukemia. 2020 May;34(5):1407-1421. doi: 10.1038/s41375-019-0690-7. Epub 2019 Dec 13.
4
Chronic Myelomonocytic leukemia: 2020 update on diagnosis, risk stratification and management.慢性髓单核细胞白血病：诊断、危险分层和治疗的 2020 年更新。
Am J Hematol. 2020 Jan;95(1):97-115. doi: 10.1002/ajh.25684.
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Thrombomodulin-expressing monocytes are associated with low-risk features in myelodysplastic syndromes and dampen excessive immune activation.表达血栓调节蛋白的单核细胞与骨髓增生异常综合征的低危特征相关，并抑制过度的免疫激活。
Haematologica. 2020 Apr;105(4):961-971. doi: 10.3324/haematol.2019.219303. Epub 2019 Jul 4.
6
Circulating T cell-monocyte complexes are markers of immune perturbations.循环 T 细胞-单核细胞复合物是免疫紊乱的标志物。
Elife. 2019 Jun 25;8:e46045. doi: 10.7554/eLife.46045.
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A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset.miR-150/TET3 通路调控小鼠和人源非经典单核细胞亚群的产生。
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