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Synthesis and biodistribution of labelled p-iodo phentermine (IP), N,N,-dimethyl-p-iodo phentermine (IDMP) and N-isopropyl-p-iodo phentermine (IIP) in rats.

作者信息

Moretti J L, Poncey M J, Roux P, Desplanches J, Dao H, Lecayon M

机构信息

Hôpital Henri Mondor, Creteil, France.

出版信息

Nucl Med Commun. 1987 Jun;8(6):441-7. doi: 10.1097/00006231-198706000-00007.

Abstract

p-Iodo-phentermine (IP) and two of its derivatives, N,N,-dimethyl-p-iodo-phentermine (IDMP) and N-isopropyl-p-iodo-phentermine (IIP) were synthesized and radiolabelled with iodine by isotopic exchange. They were evaluated as potential brain imaging agents and compared to IAMP biodistribution in rats did not show any superiority to IAMP.

摘要

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