Gorban' V A
Ontogenez. 1987 Sep-Oct;18(5):492-9.
The composition and distribution of serum proteins in blood, brain vesicles liquid, and nervous tissue has been studied in chicken embryos at 4-20 day of incubation using electrophoresis, immunoelectrophoresis, and fluorescent antibodies. At the 4-5 day of incubation, a difference in the protein composition of brain vesicles liquid and blood serum is apparent. This indicates that the border membrane of brain vesicles plays a part of the barrier. The vessels, preventing the transport of serum proteins to the nervous tissue, which are characteristic of hematoencephalic barrier of adult animals, develop in the embryo brain at the end of incubation period.
利用电泳、免疫电泳和荧光抗体技术，对孵化4至20天的鸡胚血液、脑泡液和神经组织中的血清蛋白组成及分布进行了研究。在孵化4至5天时，脑泡液和血清的蛋白质组成差异明显。这表明脑泡的边界膜起到了屏障的作用。在孵化期末，胚胎脑中会发育出血管，这些血管能够阻止血清蛋白向神经组织的运输，这是成年动物血脑屏障的特征。
