University of Nevada, Reno School of Medicine, Reno, Nevada, USA.
Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA.
Pediatr Dermatol. 2023 May-Jun;40(3):468-471. doi: 10.1111/pde.15307. Epub 2023 Mar 26.
Infantile perianal pyramidal protrusion (IPPP) is a rare benign skin condition that is typically seen in infant girls. This condition is often mistaken for other skin lesions such as acrochordons, condyloma acuminatum, and sequelae of sexual abuse. Many clinicians are unfamiliar with IPPP which can lead to aggressive workup and treatment. The purpose of this study was to elucidate demographic data, clinical features, diagnostic workup, and management of IPPP in a large cohort of patients seen at an academic medical center.
A retrospective review of patients diagnosed with IPPP at Mayo Clinic, Rochester, MN was conducted. Demographic data, examination findings, diagnostic workup, and treatments were noted.
Twenty-seven patients with IPPP, 24 of which were girls and 3 were boys from the ages of 1 day to 4 years (mean 10.8 months, median 8.6 months) were identified. Symptoms were reported in 63% (17/27) of patients. Four patients received treatment with topical corticosteroid or local anesthetic. No patient underwent skin biopsy.
IPPP is commonly observed in healthy prepubertal girls. Constipation is a common symptom. Awareness of this entity may prevent overtreatment and unnecessary evaluation.
婴儿肛周尖锥形隆起（IPPP）是一种罕见的良性皮肤疾病，通常见于女婴。这种情况常被误诊为其他皮肤病变，如软纤维瘤、尖锐湿疣和性虐待后遗症。许多临床医生不熟悉 IPPP，这可能导致过度的检查和治疗。本研究的目的是阐明在明尼苏达州罗切斯特市梅奥诊所的一个大型患者队列中，IPP 患者的人口统计学数据、临床特征、诊断检查和治疗。
对明尼苏达州罗切斯特市梅奥诊所诊断为 IPPP 的患者进行了回顾性研究。记录了人口统计学数据、检查结果、诊断检查和治疗。
共发现 27 例 IPPP 患者，其中 24 例为女孩，3 例为男孩，年龄从 1 天到 4 岁（平均 10.8 个月，中位数 8.6 个月）。63%（17/27）的患者有症状。4 例患者接受了局部皮质类固醇或局部麻醉治疗。没有患者进行皮肤活检。
IPP 常见于健康的青春期前女孩。便秘是常见症状。了解这种疾病可以避免过度治疗和不必要的评估。
