Venvertloh Emily, Karp David, Ghantarchyan Henrik H, Raoufi Kambiz
Internal Medicine, Arrowhead Regional Medical Center, Colton, USA.
Cureus. 2023 Feb 21;15(2):e35274. doi: 10.7759/cureus.35274. eCollection 2023 Feb.
Acute liver injury can be seen in a myriad of disease states such as chronic alcoholism, hepatitis, and hepatocellular carcinoma. When considering acute liver injury in a young adult, the list of differential diagnoses is much more narrow. One rare cause can be acute lymphoblastic leukemia (ALL), a hematologic malignancy that can be seen in the young adult population. We present a rare case of an 18-year-old male with no prior medical history who presented with abdominal pain and nausea. A complete workup for acute liver injury aided us in uncovering a diagnosis of B-cell ALL. This case highlights the importance of a broad differential in acute liver injury and consideration of ALL as a cause of acute liver injury, especially in young adults.
急性肝损伤可见于多种疾病状态,如慢性酒精中毒、肝炎和肝细胞癌。在考虑年轻成年人的急性肝损伤时,鉴别诊断的范围要窄得多。一种罕见的病因可能是急性淋巴细胞白血病(ALL),这是一种在年轻成年人中可见的血液系统恶性肿瘤。我们报告一例罕见病例,一名18岁男性,既往无病史,表现为腹痛和恶心。对急性肝损伤进行的全面检查帮助我们确诊为B细胞ALL。该病例强调了在急性肝损伤中进行广泛鉴别诊断以及将ALL视为急性肝损伤病因的重要性,尤其是在年轻成年人中。