Department of Radiation Oncology, Nanjing Chest Hospital, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu, China.
Technol Health Care. 2023;31(5):1759-1770. doi: 10.3233/THC-220644.
In recent years, malignant tumors have gradually become one of the main causes of death for Chinese residents, of which lung cancer ranks first in both the incidence and mortality in China.
To mine the text of traditional Chinese medicine (TCM) clinical medical cases after data cleaning, analyze it, and study the experience of TCM doctors in treating non-small cell lung cancer (NSCLC).
The applied approach was based on the data mining methods of decentralized and hierarchical system clustering of data from a drug and prescription database. This study involved 215 patients, 287 cases, and 147 types of clinical drugs.
The data analysis of the clinical treatment of NSCLC in TCM showed that Erchen Decoction was the main method for the treatment of non-small cell lung cancer in clinical treatment of non-small cell lung cancer. Junjian recipes were close to each other, with Banzhilian, Lobelia, Shanci Mushroom, Hedyotis diffusa to anticancer and detoxify.
This study analyzed the core TCM prescription for NSCLC by collecting the empirical essence and characteristics of specific medications. It has some guiding scientific significance for the clinical treatment of lung cancer.
近年来，恶性肿瘤逐渐成为中国居民主要死亡原因之一，其中肺癌无论在发病率还是死亡率上均位居中国首位。
对中医临床医案文本进行数据清洗后挖掘分析，研究中医医师治疗非小细胞肺癌（NSCLC）的经验。
采用基于药物-方剂数据库数据的分散分层系统聚类的数据挖掘方法，本研究共纳入 215 例患者，287 诊次，涉及临床用药 147 种。
中医治疗 NSCLC 的临床用药数据分析结果显示，二陈汤为治疗 NSCLC 的主要方剂，君药接近，辅以半枝莲、白花蛇舌草、山慈菇、鱼腥草抗癌解毒。
本研究通过收集特定药物的经验实质和特点，分析 NSCLC 的中医核心处方，对肺癌的临床治疗具有一定的指导科学意义。
