Sidorova N S, Kogan E M, Naumovich N G
Institute of Macromolecular Compounds, Academy of Sciences of the USSR, Leningrad.
Nucleic Acids Symp Ser. 1987(18):113-6.
It was established minimal length of continuous poly(C) sequence of poly(G).poly(C) complex required for effective interferon induction by investigation poly(G).poly(C,A) with different molar ratios of C:A varying from 10:1 to 90:1. The minimum length of the double-stranded sequence of the macromolecule complex poly(G).poly(C) is equal to at least 90-100 nucleotides. The effect of 5-halogen-polyribocytidilates on the properties of the complexes has been also investigated.
通过研究不同C:A摩尔比（从10:1到90:1）的聚（G）.聚（C，A），确定了聚（G）.聚（C）复合物连续聚（C）序列的最小长度，该长度是有效诱导干扰素所必需的。大分子复合物聚（G）.聚（C）双链序列的最小长度至少等于90 - 100个核苷酸。还研究了5 - 卤代聚核糖胞苷酸对复合物性质的影响。
