Department of Internal Medicine, Section of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam Zuidoost, The Netherlands.
Department of Public and Occupational Health, Amsterdam UMC, University of Amsterdam, Amsterdam Public Health Research Institute, Meibergdreef 9, 1105 AZ, Amsterdam Zuidoost, The Netherlands.
Eur J Prev Cardiol. 2023 Aug 1;30(10):978-985. doi: 10.1093/eurjpc/zwad089.
Hypertension is an important global health burden with major differences in prevalence among ethnic minorities compared with host populations. Longitudinal research on ethnic differences in blood pressure (BP) levels provides the opportunity to assess the efficacy of strategies aimed at mitigating gaps in hypertension control. In this study, we assessed the change in BP levels over time in a multi-ethnic population-based cohort in Amsterdam, the Netherlands.
We used baseline and follow-up data from HELIUS to assess differences in BP over time between participants of Dutch, South Asian Surinamese, African Surinamese, Ghanaian, Moroccan, and Turkish descent. Baseline data were collected between 2011 and 2015 and follow-up data between 2019 and 2021. The main outcome was ethnic differences in systolic BP (SBP) over time determined by linear mixed models adjusted for age, sex, and use of antihypertensive medication. We included 22 109 participants at baseline, from which 10 170 participants had complete follow-up data. The mean follow-up time was 6.3 (1.1) years. Compared with the Dutch population, the mean SBP increased significantly more from baseline to follow-up in Ghanaians [1.78 mmHg, 95% confidence interval (CI) 0.77-2.79], Moroccans (2.06 mmHg, 95% CI 1.23-2.90), and the Turkish population (1.30 mmHg, 95% CI 0.38-2.22). Systolic blood pressure differences were in part explained by differences in body mass index (BMI). No differences in SBP trajectory were present between the Dutch and Surinamese population.
Our findings indicate a further increase of ethnic differences in SBP among Ghanaian, Moroccan, and Turkish populations compared with the Dutch reference population that are in part attributable to differences in BMI.
高血压是一个重要的全球健康负担，少数民族的患病率与宿主人群相比存在很大差异。关于血压（BP）水平的种族差异的纵向研究为评估旨在缩小高血压控制差距的策略的效果提供了机会。在这项研究中，我们评估了荷兰阿姆斯特丹基于多民族人群的队列中 BP 水平随时间的变化。
我们使用 HELIUS 的基线和随访数据，评估了荷兰裔、南亚苏里南裔、非洲苏里南裔、加纳裔、摩洛哥裔和土耳其裔参与者之间随时间推移的 BP 差异。基线数据收集于 2011 年至 2015 年，随访数据收集于 2019 年至 2021 年。主要结局是通过线性混合模型确定的随时间推移的收缩压（SBP）的种族差异，该模型调整了年龄、性别和抗高血压药物的使用。我们纳入了 22109 名基线参与者，其中 10170 名参与者有完整的随访数据。平均随访时间为 6.3（1.1）年。与荷兰人群相比，加纳人（1.78mmHg，95%CI 0.77-2.79）、摩洛哥人（2.06mmHg，95%CI 1.23-2.90）和土耳其人（1.30mmHg，95%CI 0.38-2.22）的 SBP 从基线到随访的增加幅度明显更大。SBP 差异部分由体重指数（BMI）的差异解释。荷兰和苏里南人群之间 SBP 轨迹没有差异。
我们的研究结果表明，与荷兰参考人群相比，加纳人、摩洛哥人和土耳其人 SBP 的种族差异进一步增加，部分归因于 BMI 的差异。
