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利用多元线性回归模型确定翻修全膝关节置换术中的关节线:尸体研究。

Identification of the joint line in revision total knee arthroplasty using a multiple linear regression model: a cadaveric study.

机构信息

Arthritis Clinic and Research Center, Peking University People's Hospital, Peking University, No. 11, Xizhimen South Street, Xicheng District, Beijing, 100044, People's Republic of China.

Department of Orthopedics, Jin Xiang People's Hospital, Jining Medical University, No. 117, Jinfeng East Road, Jinxiang County, 272100, Shandong Province, People's Republic of China.

出版信息

Arch Orthop Trauma Surg. 2023 Aug;143(8):5239-5248. doi: 10.1007/s00402-023-04792-3. Epub 2023 Mar 27.

DOI:10.1007/s00402-023-04792-3
PMID:36971801
Abstract

INTRODUCTION

The results of revision total knee arthroplasty (rTKA) may be compromised by excessive joint line (JL) elevation. It is critical but challenging in reestablishing the JL in rTKA. Previous studies have confirmed that, biomechanically and clinically, JL elevation should not exceed 4 mm. Image-based studies described several approaches to locate the JL intraoperatively, however magnification errors could occur. In this cadaveric study, we aim to define an accurate and reliable method to determine the JL.

MATERIALS AND METHODS

Thirteen male and eleven female cadavers were used, with an average age of death being 48.3 years. The transepicondylar width (TEW), the distance from the medial (MEJL) and lateral (LEJL) epicondyle, adductor tubercle (ATJL), fibular head (FHJL) and tibial tubercle (TTJL) to the JL were measured in 48 knees. Intra- and interobserver reliability and validity were tested prior to any additional analysis. Pearson correlation and linear regression analysis were used to examine the correlations between landmark-JL distances (LEJL, MEJL, ATJL, FHJL and TTJL) and the TEW, and to further derive models for intraoperative JL determination. The accuracy of different models, quantified by errors between estimated and measured landmark-JL distances, was compared using the Friedman and post hoc Dunn tests.

RESULTS

The intra- and inter-observer measurements for TEW, MEJL, LEJL, ATJL, TTJL and FHJL did not differ significantly (p > 0.05). Between genders, significant differences were found on TEW, MEJL, LEJL, ATJL, FHJL and TTJL (p < 0.05). There was no association between TEW and either FHJL or TTJL (p > 0.05), while ATJL, MEJL, and LEJL were found to be correlated with TEW (p < 0.05). Six models were derived: (1) MEJL = 0.37TEW (r = 0.384), (2) LEJL = 0.28TEW (r = 0.380), (3) ATJL = 0.47TEW (r = 0.608), (4) MEJL = 0.413TEW - 4.197 (R = 0.473), (5) LEJL = 0.236TEW + 3.373 (R = 0.326), (6) ATJL = 0.455TEW + 1.440 (R = 0.556). Errors were defined as deviations between estimated and actual landmark-JL distances. The mean absolute value of the errors, created by Model 1-6 was 3.18 ± 2.25, 2.53 ± 2.15, 2.64 ± 2.2, 1.85 ± 1.61, 1.60 ± 1.59 and 1.71 ± 1.5, respectively. The error could be limited to 4 mm in 72.9%, 83.3%, 72.9%, 87.5%, 87.5%, and 93.8% of the cases by referencing Model 1-6, respectively.

CONCLUSION

Compared to previous image-based measurements, the current cadaveric study most closely resembles a realistic view of intraoperative settings and could circumvents magnification errors. We recommend using Model 6, the JL can be best estimated by referencing the AT and the ATJL can be calculated as ATJL (mm) = 0.455*TEW (mm) + 1.440 (mm).

摘要

简介

翻修全膝关节置换术(rTKA)的结果可能因关节线(JL)过度抬高而受到影响。在 rTKA 中重新建立 JL 至关重要,但具有挑战性。先前的研究已经证实,从生物力学和临床角度来看,JL 抬高不应超过 4 毫米。基于图像的研究描述了几种术中定位 JL 的方法,然而可能会出现放大误差。在这项尸体研究中,我们旨在确定一种准确可靠的方法来确定 JL。

材料和方法

使用了 13 名男性和 11 名女性尸体,平均死亡年龄为 48.3 岁。在 48 个膝关节中测量了经髁宽度(TEW)、内侧(MEJL)和外侧(LEJL)髁、内收结节(ATJL)、腓骨头(FHJL)和胫骨结节(TTJL)到 JL 的距离。在进行任何额外分析之前,测试了内、观察者之间的可靠性和有效性。使用 Pearson 相关性和线性回归分析检查了标志点-JL 距离(LEJL、MEJL、ATJL、FHJL 和 TTJL)与 TEW 之间的相关性,并进一步得出了用于术中 JL 确定的模型。使用 Friedman 和事后 Dunn 检验比较了不同模型的准确性,通过估计和测量标志点-JL 距离之间的误差来量化。

结果

TEW、MEJL、LEJL、ATJL、TTJL 和 FHJL 的内、观察者测量值之间没有显著差异(p > 0.05)。在性别之间,TEW、MEJL、LEJL、ATJL、FHJL 和 TTJL 存在显著差异(p < 0.05)。TEW 与 FHJL 或 TTJL 之间没有关联(p > 0.05),而 ATJL、MEJL 和 LEJL 与 TEW 相关(p < 0.05)。得出了六个模型:(1)MEJL=0.37TEW(r=0.384),(2)LEJL=0.28TEW(r=0.380),(3)ATJL=0.47TEW(r=0.608),(4)MEJL=0.413TEW-4.197(R=0.473),(5)LEJL=0.236TEW+3.373(R=0.326),(6)ATJL=0.455TEW+1.440(R=0.556)。误差定义为估计值和实际标志点-JL 距离之间的偏差。模型 1-6 产生的平均绝对误差值分别为 3.18±2.25、2.53±2.15、2.64±2.2、1.85±1.61、1.60±1.59 和 1.71±1.5。通过参考模型 1-6,分别可以将 72.9%、83.3%、72.9%、87.5%、87.5%和 93.8%的病例的误差限制在 4 毫米以内。

结论

与之前基于图像的测量相比,当前的尸体研究最接近术中设置的实际情况,可以避免放大误差。我们建议使用模型 6,通过参考 AT 和 ATJL 可以最佳地估计 JL,并且可以计算出 ATJL(mm)=0.455*TEW(mm)+1.440(mm)。

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Knee joint line related to bony landmarks of the knee: a radiologic study in a Thai population.膝关节间隙与膝关节骨性标志的关系:泰国人群的影像学研究
Knee Surg Relat Res. 2022 Feb 15;34(1):5. doi: 10.1186/s43019-022-00135-5.
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The reliability of adductor tubercle as an anatomical landmark for joint line restoration in revision knee arthroplasty: a systematic review.
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Ann Transl Med. 2021 Jan;9(1):71. doi: 10.21037/atm-20-3681.
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