• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

苯二氮䓬类药物的长期使用:持续存在的问题。

Chronic use of benzodiazepines: The problem that persists.

机构信息

Veterans Affairs Palo Alto Health Care System, Menlo Park, CA, USA.

Yale School of Medicine, New Haven, CT, USA.

出版信息

Int J Psychiatry Med. 2023 Sep;58(5):426-432. doi: 10.1177/00912174231166252. Epub 2023 Mar 27.

DOI:10.1177/00912174231166252
PMID:36972700
Abstract

Though clinical guidelines and policies discourage the chronic prescribing of benzodiazepines, rates of prescribing have continued to rise in the United States with an estimated 65.9 million office visits per year made for this purpose. Quietly, we have become a nation on benzodiazepines. There are numerous reasons for this discrepancy between official recommendations on the one hand, and actual clinical practice on the other. Drawing from the literature, we argue that while patients and providers both shoulder some of the responsibility, they cannot be solely blamed. Rather, policies and guidelines regarding benzodiazepine prescribing have become out of touch with the clinical reality that benzodiazepines are now deeply entrenched in modern medicine. We propose that guidelines regarding benzodiazepines need to reconsider how to apply concepts such as harm reduction and other lessons learned in the opioid epidemic in order to help physicians manage this increasingly pressing problem affecting millions of Americans.

摘要

尽管临床指南和政策不鼓励长期开具苯二氮䓬类药物,但美国的开具此类药物的比率仍在持续上升,每年为此目的的就诊估计有 6590 万次。我们悄悄地成为了一个依赖苯二氮䓬类药物的国家。这种官方建议与实际临床实践之间的差异有很多原因。从文献中可以看出,尽管患者和医务人员都有一定的责任,但不能仅仅归咎于他们。相反,关于苯二氮䓬类药物处方的政策和指南已经与苯二氮䓬类药物现在已深深扎根于现代医学这一临床现实脱节。我们提出,关于苯二氮䓬类药物的指南需要重新考虑如何应用减少危害等概念,以及在阿片类药物流行中吸取的其他经验教训,以帮助医生应对这一影响数百万美国人的日益紧迫的问题。

相似文献

1
Chronic use of benzodiazepines: The problem that persists.苯二氮䓬类药物的长期使用:持续存在的问题。
Int J Psychiatry Med. 2023 Sep;58(5):426-432. doi: 10.1177/00912174231166252. Epub 2023 Mar 27.
2
Controlled Substance Prescribing Patterns--Prescription Behavior Surveillance System, Eight States, 2013.受控物质处方模式 - 处方行为监测系统,八个州,2013 年。
MMWR Surveill Summ. 2015 Oct 16;64(9):1-14. doi: 10.15585/mmwr.ss6409a1.
3
Patterns in Outpatient Benzodiazepine Prescribing in the United States.美国门诊苯二氮䓬类药物处方模式。
JAMA Netw Open. 2019 Jan 4;2(1):e187399. doi: 10.1001/jamanetworkopen.2018.7399.
4
Trends in opioid prescribing and co-prescribing of sedative hypnotics for acute and chronic musculoskeletal pain: 2001-2010.2001 - 2010年急性和慢性肌肉骨骼疼痛的阿片类药物处方及镇静催眠药联合处方趋势
Pharmacoepidemiol Drug Saf. 2015 Aug;24(8):885-92. doi: 10.1002/pds.3776. Epub 2015 Apr 22.
5
An Examination of Concurrent Opioid and Benzodiazepine Prescribing in 9 States, 2015.9 个州 2015 年阿片类药物与苯二氮䓬类药物同时处方情况调查
Am J Prev Med. 2019 Nov;57(5):629-636. doi: 10.1016/j.amepre.2019.06.007. Epub 2019 Sep 27.
6
Coprescribing of Benzodiazepines and Opioids in Older Adults: Rates, Correlates, and National Trends.老年人苯二氮䓬类和阿片类药物的联合处方:比率、相关性和国家趋势。
J Gerontol A Biol Sci Med Sci. 2019 Nov 13;74(12):1910-1915. doi: 10.1093/gerona/gly283.
7
Prescribing of Opioids and Benzodiazepines Among Patients With History of Overdose.有过过量用药史的患者中阿片类药物和苯二氮䓬类药物的处方情况。
J Addict Med. 2019 Sep/Oct;13(5):396-402. doi: 10.1097/ADM.0000000000000513.
8
Vital signs: variation among States in prescribing of opioid pain relievers and benzodiazepines - United States, 2012.生命体征:2012 年美国各州阿片类止痛药和苯二氮䓬类药物处方差异。
MMWR Morb Mortal Wkly Rep. 2014 Jul 4;63(26):563-8.
9
Mandatory Review of Prescription Drug Monitoring Program Before Issuance of a Controlled Substance Results in Overall Reduction of Prescriptions Including Opioids and Benzodiazepines.在发放受控物质之前,对处方药物监测计划进行强制性审查,可全面减少包括阿片类药物和苯二氮䓬类药物在内的处方数量。
Pain Physician. 2020 Jun;23(3):299-304.
10
Rates of Physician Coprescribing of Opioids and Benzodiazepines After the Release of the Centers for Disease Control and Prevention Guidelines in 2016.2016 年疾病预防控制中心发布指南后,医生同时开处阿片类药物和苯二氮䓬类药物的比率。
JAMA Netw Open. 2019 Aug 2;2(8):e198325. doi: 10.1001/jamanetworkopen.2019.8325.

引用本文的文献

1
Experiences of long-term benzodiazepine use and addiction amid changes in guidelines for the prescription of narcotic drugs: a qualitative study.麻醉药品处方指南变化背景下长期使用苯二氮䓬类药物及成瘾的经历:一项定性研究
BMC Public Health. 2025 Aug 5;25(1):2652. doi: 10.1186/s12889-025-23920-9.
2
Prescribing and deprescribing guidance for benzodiazepine and benzodiazepine receptor agonist use in adults with depression, anxiety, and insomnia: an international scoping review.苯二氮䓬类药物及苯二氮䓬受体激动剂在患有抑郁症、焦虑症和失眠症的成人中使用的处方及减药指南:一项国际范围综述
EClinicalMedicine. 2024 Mar 13;70:102507. doi: 10.1016/j.eclinm.2024.102507. eCollection 2024 Apr.