Novembre E, Veneruso G, Sabatini C, Bonazza P, Bernardini R, Vierucci A
Istituto di Pediatria Cesare Cocchi, Ospedale Meyer, Firenze, Italia.
Pediatr Med Chir. 1987 Jul-Aug;9(4):399-404.
Both upper and lower respiratory tracts can be affected by food allergy. In infants these symptoms may be due exclusively to food allergy or may result from the effect of food allergy and another co-factor (gastro-esophageal reflux, immunodeficiency, concomitant allergy to inhalants, etc.). The incidence of food-induced asthma is not well know. In this study, using open and double blind food challenge, we found that the incidence of IgE-mediated, food-induced asthma in children is 5.7%. The most offending foods were milk, eggs, and peanuts. Food allergy respiratory symptoms were almost always associated with other clinical manifestations (cutaneous, gastrointestinal). In fact we have been able to demonstrate only one isolated case of cough due to food allergy. It follows that the recognition of food dependent-IgE-mediated asthma is essentially limited to these cases characterized by food allergy with asthmatic expression.
上呼吸道和下呼吸道均可受到食物过敏的影响。在婴儿中，这些症状可能完全由食物过敏引起，也可能是食物过敏与另一种共同因素（胃食管反流、免疫缺陷、同时对吸入物过敏等）共同作用的结果。食物诱发哮喘的发病率尚不清楚。在本研究中，通过开放和双盲食物激发试验，我们发现儿童中IgE介导的食物诱发哮喘的发病率为5.7%。最常见的致敏食物是牛奶、鸡蛋和花生。食物过敏引起的呼吸道症状几乎总是与其他临床表现（皮肤、胃肠道）相关。事实上，我们仅证实了1例因食物过敏引起的孤立咳嗽病例。由此可见，对食物依赖性IgE介导的哮喘的认识基本上仅限于这些以食物过敏伴哮喘表现为特征的病例。
