Miller-Larsson A
Biol Cybern. 1986;53(5):307-21. doi: 10.1007/BF00336563.
The theoretical field of a motor unit (MU) action potential (MUP) was considered. It has been proved that in normal muscles the shape of a smooth threephasic MUP curve is determined mostly by the spatial distribution of MU muscle fibres. Phenomena called "time dispersion" are of prime importance in pathology, where they complicate normal threephasic MUP. Amplitudes and time parameters of model threephasic MUP were analyzed as a function of the radial distance R from the geometrical centre of the motor unit territory (MUT) and approximated by mathematical expressions. It appeared that analysis of radial variability of MUP curve allows conclusions to be made about the MUT size and the spatial distribution of MU muscle fibres. These anatomical features of a MU are often changed in pathological muscles, thus the proposed methods of their evaluation could be helpful in diagnosis of neuromuscular diseases.
研究了运动单位（MU）动作电位（MUP）的理论场。已证明，在正常肌肉中，平滑的三相MUP曲线形状主要由运动单位肌纤维的空间分布决定。在病理学中，称为“时间离散”的现象至关重要，它们使正常的三相MUP变得复杂。分析了模型三相MUP的幅度和时间参数作为距运动单位区域（MUT）几何中心的径向距离R的函数，并通过数学表达式进行近似。结果表明，对MUP曲线径向变异性的分析可以得出关于MUT大小和MU肌纤维空间分布的结论。运动单位的这些解剖学特征在病理性肌肉中经常发生变化，因此所提出的评估方法可能有助于神经肌肉疾病的诊断。
