Department of Otolaryngology, Örebro University Hospital, Örebro, Sweden;
Örebro University, Örebro, Sweden.
Anticancer Res. 2023 Apr;43(4):1853-1855. doi: 10.21873/anticanres.16339.
BACKGROUND/AIM: Radioactive iodine (RAI) treatment is a cornerstone of treatment of differentiated thyroid carcinoma. Although serious RAI-related complications are uncommon, there have been reports of airway emergencies. Here, a life-threatening airway complication after RAI treatment is reported and previously reported cases are reviewed.
A 79-year old man with Hürthle cell carcinoma and a remnant thyroid lobe after surgery developed an edema compromising the airway two days after receiving radioactive iodine treatment. An emergency awake intubation and tracheostomy were performed. He could be successfully de-cannulated 17 days later with no long-term complications.
Although rare, life-threatening airway complications after radioactive iodine treatment, especially with high dose treatment in patients with remaining thyroid tissue, can occur and these patients should be supervised where these complications can be managed.
背景/目的：放射性碘（RAI）治疗是分化型甲状腺癌治疗的基石。尽管严重的 RAI 相关并发症并不常见，但已有气道急症的报告。在此，报告一例 RAI 治疗后危及生命的气道并发症，并复习以往报告的病例。
一名 79 岁男性，患有 Hurthle 细胞癌，手术后残留甲状腺组织，在接受放射性碘治疗两天后出现气道水肿，导致气道阻塞。紧急在清醒状态下进行气管插管和气管切开术。17 天后成功拔管，无长期并发症。
尽管罕见，但 RAI 治疗后可发生危及生命的气道并发症，特别是在残留甲状腺组织的患者中接受高剂量治疗时，可能会发生这些并发症，应进行密切监测并能对此类并发症进行处理。
