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维生素 D 缺乏与复发性扁桃体炎的关系。

Association Between Vitamin D Deficiency and Recurrent Tonsillitis.

机构信息

Department of ENT, Head and Neck Surgery, Kathmandu Medical College Teaching Hospital.

出版信息

J Nepal Health Res Counc. 2023 Mar 10;20(3):731-733. doi: 10.33314/jnhrc.v20i3.4223.

DOI:10.33314/jnhrc.v20i3.4223
PMID:36974865
Abstract

BACKGROUND

Tonsillitis is defined as an inflammation of the tonsils characterized by signs of tonsillar erythema and exudates and recurrent tonsillitis is at least 7 episodes of acute tonsillitis in a year, or a minimum of 5 episodes in a year for 2 consecutive years, or at least 3 episodes in a year for 3 consecutive years. There are many research that have hypothesized the association of low level of Vitamin D and recurrent attacks of acute tonsillitis.

METHODS

A single centre prospective, cross sectional analytical study was conducted from 2021 June to 2022 March in Department of ENT and Head and Neck surgery in Kathmandu Medical College Teaching Hospital. The study participants were recruited from ENT Head and Neck OPD and the data on number of episodes of recurrent attacks of tonsillitis and serum level of Vitamin D were collected.

RESULTS

78.8% of patients with tonsillitis had low level of serum Vitamin D (less than 30ng/ml) and 21.2% had optimal level of serum Vitamin D (more than 30ng/ml). The incidence of recurrent tonsillitis was 40.9% in patients with low level of Vitamin D where as the incidence of recurrent tonsillitis was 18.1% in patients with optimal level of Vitamin D.

CONCLUSIONS

The low serum level of Vitamin D was found to be associated with recurrent episodes of tonsillitis.

摘要

背景

扁桃体炎是指扁桃体炎症,其特征为扁桃体红斑和渗出物,并伴有复发性扁桃体炎,即每年至少发生 7 次急性扁桃体炎,或连续 2 年每年至少发生 5 次,或连续 3 年每年至少发生 3 次。有许多研究假设维生素 D 水平低与急性扁桃体炎反复发作有关。

方法

2021 年 6 月至 2022 年 3 月,在加德满都医学院教学医院耳鼻喉头颈外科进行了一项单中心前瞻性横断面分析研究。研究参与者从耳鼻喉头颈外科门诊招募,收集了反复发作的扁桃体炎次数和血清维生素 D 水平的数据。

结果

78.8%的扁桃体炎患者血清维生素 D 水平较低(<30ng/ml),21.2%的患者血清维生素 D 水平正常(>30ng/ml)。低维生素 D 组的复发性扁桃体炎发生率为 40.9%,而维生素 D 水平正常组的复发性扁桃体炎发生率为 18.1%。

结论

低血清维生素 D 水平与扁桃体炎反复发作有关。

相似文献

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Histopathological role of vitamin D deficiency in recurrent/chronic tonsillitis pathogenesis: Vascular epithelial growth factor-mediated angiogenesis in tonsil.维生素 D 缺乏在复发性/慢性扁桃体炎发病机制中的组织病理学作用:扁桃体中血管内皮生长因子介导的血管生成。
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