Department of Otolaryngology, Pamukkale University, Faculty of Medicine, Denizli, Turkey.
J Int Adv Otol. 2023 Mar;19(2):140-148. doi: 10.5152/iao.2023.22697.
Surgical tympanostomy tube insertion is a standard procedure in Otitis media with effusion after proper follow-up. During the surgery, the presence of serous or mucoid fluids, atelectatic tympanic membrane, or empty ear may be observed, despite all patients having the same diagnosis. A better method based on a non-invasive approach can help avoid unnecessary surgery. This study aimed to compare surgically confirmed otitis media with effusion with wideband tympanometry and absorbance tests.
A total of 122 children diagnosed with otitis media with effusion were included. Eighty healthy children were included as controls. Ears were divided into 4 groups: serous, mucoid, atelectasis, and empty. Resonance frequency, 226 Hz and 1000 Hz compliance, wideband peak pressure, and absorbance data were used for comparison.
The most practical tests were the average of 500, 1000, and 2000 Hz absorbance according to positive likelihood ratio (4.8) and model 2 according to negative likelihood ratio (0.11). It was better than the standard 226 Hz and 1000 Hz compliance tests. Although some statistically significant parameters were observed between serous fluid and empty ear, they were not sufficiently impactful for a differential diagnosis. No parameter could help us differentiate between serous and mucous fluids.
According to negative likelihood ratio (0.11), a person with normal middle ear is 9 times more likely to have negative test with the use of resonance frequency, wideband tympanometry, and average absorbance together. To differentiate serous fluid from the empty ear, using only 226 Hz or 1000 Hz compliance for surgical indication can potentially cause wrong decisions according to negative likelihood ratios.
在适当的随访后,分泌性中耳炎患者行鼓膜切开置管术是一种标准的治疗方法。然而,尽管所有患者的诊断相同,在手术过程中仍可能观察到浆液性或黏液性液体、鼓膜萎陷或空耳等表现。因此,我们需要一种基于非侵入性方法的更好的方法来避免不必要的手术。本研究旨在比较鼓室压图和声导抗宽频测试与手术确诊的分泌性中耳炎的相关性。
共纳入 122 例分泌性中耳炎患儿,80 例健康儿童作为对照。将耳朵分为 4 组:浆液性、黏液性、鼓膜萎缩和空耳。比较共振频率、226 Hz 和 1000 Hz 顺应性、宽频带峰值压力和吸收率数据。
根据阳性似然比(4.8),最实用的测试是 500、1000 和 2000 Hz 吸收率的平均值,根据负似然比(0.11),模型 2 也优于标准的 226 Hz 和 1000 Hz 顺应性测试。虽然在浆液性积液和空耳之间观察到一些具有统计学意义的参数,但它们不足以进行鉴别诊断。没有任何参数可以帮助我们区分浆液性和黏液性积液。
根据负似然比(0.11),正常中耳的人在使用共振频率、宽频鼓室压图和声导抗吸收率联合测试时,其测试结果为阴性的可能性是进行手术的 9 倍。为了将浆液性积液与空耳区分开来,仅使用 226 Hz 或 1000 Hz 顺应性作为手术指征,根据负似然比,可能会导致错误的决策。