Sarcoma Surgery Unit, Instituto Oncologico Fundación Arturo Lopez Perez (Falp), Santiago 7500691, Chile.
Vascular Surgery Unit, Instituto Oncologico Fundación Arturo Lopez Perez (Falp), Santiago 7500691, Chile.
Curr Oncol. 2023 Mar 20;30(3):3500-3515. doi: 10.3390/curroncol30030266.
Retroperitoneal sarcomas (RPSs) are locally aggressive tumors that can compromise major vessels of the retroperitoneum including the inferior vena cava, aorta, or main tributary vessels. Vascular involvement can be secondary to the tumor's infiltrating growth pattern or primary vascular origin. Surgery is still the mainstay for curing this disease, and resection of RPSs may include major vascular resections to secure adequate oncologic results. Our improved knowledge in the tumor biology of RPSs, in conjunction with the growing surgical expertise in both sarcoma and vascular surgical techniques, has allowed for major vascular reconstructions within multi-visceral resections for RPSs with good perioperative results. This complex surgical approach may include the combined work of various surgical subspecialties.
腹膜后肉瘤(RPS)是一种局部侵袭性肿瘤,可累及腹膜后的大血管,包括下腔静脉、主动脉或主要支流血管。血管受累可能是由于肿瘤的浸润性生长模式或原发性血管起源。手术仍然是治疗这种疾病的主要方法,RPS 的切除可能包括大血管切除,以确保获得足够的肿瘤学结果。我们对 RPS 肿瘤生物学的认识不断提高,加上在肉瘤和血管外科技术方面的外科专业知识不断增长,使得在多脏器切除的情况下对 RPS 进行大血管重建成为可能,且围手术期结果良好。这种复杂的手术方法可能需要多个外科亚专业的共同努力。