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人类呼吸道纤毛的顶端结构。

Apical structure of human respiratory cilia.

作者信息

Foliguet B, Puchelle E

出版信息

Bull Eur Physiopathol Respir. 1986 Jan-Feb;22(1):43-7.

PMID:3697548
Abstract

The apical structure of human respiratory cilia was studied using thin and thick sectioning techniques. The distal end of the mature cilium is narrowed and presents dense material and a crown-shaped glycocalyx. The crown is composed of three to seven bristles, having a mean length of 31 nm and showing a periodic structure. The capping structure of the apical part of human respiratory cilia is composed of a plate and an electron-dense cap tightly bound to the central and to each of the nine peripheral A microtubules. Lateral spokes link the peripheral microtubules to the internal ciliary plasma membrane and dense filaments radiate from the dense cap to the ciliary crown. These ciliary apical structures may be involved in several functions associated with microtubule assembly as well as ciliary movement and mucociliary transport.

摘要

采用薄切片和厚切片技术对人呼吸道纤毛的顶端结构进行了研究。成熟纤毛的远端变窄,呈现致密物质和冠状糖萼。冠由三到七根刷毛组成,平均长度为31纳米,并呈现出周期性结构。人呼吸道纤毛顶端部分的帽状结构由一个板和一个紧密结合在中央微管和九根外周A微管中的每一根上的电子致密帽组成。侧辐将外周微管连接到纤毛内部的质膜,致密细丝从致密帽辐射到纤毛冠。这些纤毛顶端结构可能参与了与微管组装以及纤毛运动和黏液纤毛运输相关的多种功能。

相似文献

1
Apical structure of human respiratory cilia.人类呼吸道纤毛的顶端结构。
Bull Eur Physiopathol Respir. 1986 Jan-Feb;22(1):43-7.
2
Ultrastructural observations on basal apparatus of respiratory cilia in immotile cilia syndrome.不动纤毛综合征中呼吸纤毛基部装置的超微结构观察
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3
[Ciliary disorders of the bronchi in children].[儿童支气管的纤毛疾病]
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4
[Sperm flagella and cilia with pathologic motility and ultrastructure].[具有病理性运动和超微结构的精子鞭毛和纤毛]
Schweiz Med Wochenschr. 1984 Oct 20;114(42):1442-50.
5
[How useful is the ultrastructural study of the cilia of the respiratory tract in the diagnosis of an immotile cilia syndrome?].[呼吸道纤毛超微结构研究在诊断纤毛不动综合征中具有多大作用?]
Schweiz Med Wochenschr. 1984 May 5;114(18):610-9.
6
The structure of the tips of mammalian respiratory cilia.哺乳动物呼吸道纤毛尖端的结构。
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7
Ultrastructural pathology of cilia in the immotile cilia syndrome.
Perspect Pediatr Pathol. 1984 Summer;8(2):133-61.
8
[Clinical and ultrastructural evaluation of nasal mucociliary function in HIV-positive patients. Preliminary investigation].[HIV阳性患者鼻黏膜纤毛功能的临床与超微结构评估。初步调查]
Acta Otorrinolaringol Esp. 1997 Jan-Feb;48(1):27-30.
9
Supernumerary microtubules in the cilia of two siblings causing "immotile cilia syndrome".两名患有“不动纤毛综合征”的兄弟姐妹的纤毛中存在多余的微管。
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Centrosomal protein CEP104 (Chlamydomonas FAP256) moves to the ciliary tip during ciliary assembly.中心体蛋白 CEP104(衣藻 FAP256)在纤毛组装过程中向纤毛尖端移动。
J Cell Sci. 2013 Nov 1;126(Pt 21):5018-29. doi: 10.1242/jcs.133439. Epub 2013 Aug 22.
2
Sentan: a novel specific component of the apical structure of vertebrate motile cilia.森坦:脊椎动物运动纤毛顶端结构的一种新型特定成分。
Mol Biol Cell. 2008 Dec;19(12):5338-46. doi: 10.1091/mbc.e08-07-0691. Epub 2008 Oct 1.
3
Claws of cilia: further observation of ciliated epithelium in neurenteric cyst.
纤毛之爪:神经肠囊肿中纤毛上皮的进一步观察
Virchows Arch A Pathol Anat Histopathol. 1991;418(3):263-5. doi: 10.1007/BF01606065.
4
Ciliary claws: their existence in various epithelial cysts of the central nervous system.睫状爪:它们在中枢神经系统各种上皮囊肿中的存在情况。
Acta Neuropathol. 1992;84(4):453-6. doi: 10.1007/BF00227675.