Venugopala Delanthabettu, Dsouza Nikhil Victor, Acharya Vishak, Rai Maneesh, Venkataramana Chaithra Gowthuvalli, Boussios Stergios
Department of Internal Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Mangalore 576104, India.
Department of Respiratory Medicine, Medway NHS Foundation Trust, Windmill Road, Gillingham ME7 5NY, UK.
Hematol Rep. 2023 Mar 2;15(1):166-171. doi: 10.3390/hematolrep15010017.
Non-Hodgkin's lymphoma presenting as a primary cardiac lymphoma (PCL) is extremely unusual. Having a predilection for the right side of the heart and accounting for 1% of all cardiac tumours, the difficulty in diagnosing the lesion, owing to the location and vague presenting symptoms and signs, often leads to delayed diagnosis and poor prognosis. In our case report, a middle-aged male was diagnosed with PCL presenting as pyrexia of unknown origin with the help of F18-fluorodeoxyglucose positron emission tomography (18 FDG-PET). PET-CT is an invaluable tool in patients with pyrexia of unknown origin (PUO), especially caused by neoplasms as it helps in localizing the target lesion, aiding in selecting the appropriate intervention for rapid tissue diagnosis. This case serves to sensitize the physicians of PCL presenting with PUO and mimicking a relatively common cardiac tumour such as atrial myxoma.
表现为原发性心脏淋巴瘤（PCL）的非霍奇金淋巴瘤极为罕见。它倾向于发生在心脏右侧，占所有心脏肿瘤的1%，由于病变位置以及症状和体征不明确，诊断该病变存在困难，这常常导致诊断延迟和预后不良。在我们的病例报告中，一名中年男性借助F18-氟脱氧葡萄糖正电子发射断层扫描（18 FDG-PET）被诊断为表现为不明原因发热的PCL。PET-CT对于不明原因发热（PUO）患者，尤其是由肿瘤引起的患者，是一种非常有价值的工具，因为它有助于定位目标病变，辅助选择合适的干预措施以进行快速组织诊断。该病例旨在提高医生对表现为PUO且酷似相对常见的心脏肿瘤如心房黏液瘤的PCL的认识。
