School of Pharmacy, Institute of Clinical Sciences, College of Medical and Dental Sciences, Sir Robert Aitken Institute for Medical Research, University of Birmingham, Birmingham, B15 2TT, UK.
Pharmaceutical Care Department, King Fahad Military Medical Complex (KFMMC), Medical Department, Ministry of Defense, Dhahran, Saudi Arabia.
Int J Clin Pharm. 2023 Jun;45(3):681-688. doi: 10.1007/s11096-023-01555-3. Epub 2023 Mar 28.
Despite their effectiveness and ease of use, medication errors have been reported to be highly prevalent with direct-acting oral anticoagulants (DOAC).
The aim of this study was to explore views and experiences of pharmacists on contributory factors and mitigation strategies around medication errors in relation to DOAC.
This study used a qualitative design. Semi-structured interviews were conducted with hospital pharmacists in Saudi Arabia. The interview topic guide was developed based on previous literature and Reason's Accident Causation Model. All interviews were transcribed verbatim and MAXQDA Analytics Pro 2020 was used to thematically analyse the data (VERBI Software).
Twenty-three participants representing a range of experiences participated. The analysis recognised three major themes: (a) enablers and barriers faced by pharmacists in promoting safe utilisation of DOAC, such as opportunities to conduct risk assessments and offer patient counselling (b) factors related to other healthcare professionals and patients, such as opportunities for effective collaborations and patient health literacy; and (c) effective strategies to promote DOAC safety such as empowering the role of pharmacists, patient education, opportunities for risk assessments, multidisciplinary working and enforcement of clinical guidelines and enhanced roles of pharmacists.
Pharmacists believed that enhanced education of healthcare professionals and patients, development and implementation of clinical guidelines, improvement of incident reporting systems, and multidisciplinary team working could be effective strategies to reduce DOAC-related errors. In addition, future research should utilise multifaceted interventions to reduce error prevalence.
尽管直接作用的口服抗凝剂(DOAC)有效且使用方便,但据报道,它们的用药错误发生率很高。
本研究旨在探讨药剂师对 DOAC 相关用药错误的促成因素和缓解策略的看法和经验。
本研究采用定性设计。在沙特阿拉伯的医院药剂师中进行了半结构式访谈。访谈主题指南是基于先前的文献和 Reason 的事故因果模型制定的。所有访谈均逐字转录,并使用 MAXQDA Analytics Pro 2020 对数据进行主题分析(VERBI 软件)。
共有 23 名代表不同经验的参与者参加。分析确定了三个主要主题:(a)药剂师在促进 DOAC 安全使用方面面临的促成因素和障碍,例如进行风险评估和提供患者咨询的机会;(b)与其他医疗保健专业人员和患者相关的因素,如有效合作和患者健康素养的机会;以及(c)促进 DOAC 安全的有效策略,如增强药剂师的角色、患者教育、风险评估机会、多学科工作以及执行临床指南和增强药剂师的作用。
药剂师认为,加强医疗保健专业人员和患者的教育、制定和实施临床指南、改进不良事件报告系统以及多学科团队合作是减少 DOAC 相关错误的有效策略。此外,未来的研究应利用多方面的干预措施来降低错误发生率。