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Antisera to an axolemma-enriched fraction inhibit neurite outgrowth and destroy axons in vitro.

作者信息

Bourdette D N, Seil F J, Bigbee J W, DeVries G H, Garwood M M, Agrawal H C

出版信息

Brain Res. 1986 Feb 26;366(1-2):333-7. doi: 10.1016/0006-8993(86)91313-2.

Abstract

Antisera prepared to an axolemma-enriched fraction derived from rat brain inhibited neurite outgrowth and destroyed mature axons in spinal cord-dorsal root ganglia cultures. Similar antibody-mediated anti-axon effects may be important in some diseases of the human nervous system.

摘要

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